> Interleukin 6 receptor (IL6R)
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UGID:150296     UniGene Hs.135087     Homo sapiens (human)   IL6R Order cDNA clone, Links
Interleukin 6 receptor (IL6R)

Human protein-coding gene IL6R. Represented by 179 ESTs from 107 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 150296 - Hs.135087]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000556.1 IL6R gene product H. sapiens 100.0 467
XP_524889.3 PREDICTED: interleukin-6 receptor subunit alpha isoform 2 P. troglodytes 99.8 467
NP_034689.2 interleukin-6 receptor subunit alpha precursor M. musculus 55.6 459
Other hits (2 of 11) [Show all]SpeciesId(%)Len(aa)
XP_003892768.1 PREDICTED: interleukin-6 receptor subunit alpha isoform 1 P. anubis 99.2 467
XP_001114404.1 PREDICTED: interleukin-6 receptor subunit alpha M. mulatta 98.9 467

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; blood; placenta; larynx; uncharacterized tissue; prostate; muscle; liver; skin; bone marrow; kidney; heart; mouth; testis; spleen; mammary gland; uterus; lung; lymph node; connective tissue; embryonic tissue; thymus; pancreas; trachea; eye; epididymis; bone; intestine; stomach; vascular; pharynx; ganglia; ovary
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q21
UniSTS entry: Chr 1 D1S2375 [Map Viewer]
UniSTS entry: Chr 1 SHGC-34808 [Map Viewer]
UniSTS entry: Chr 1 RH69094 [Map Viewer]
UniSTS entry: Chr 1 PMC150666P1
UniSTS entry: GDB:353581
UniSTS entry: Chr 1 RH16347 [Map Viewer]
UniSTS entry: GDB:386402
UniSTS entry: Chr 1 L17705
UniSTS entry: Chr 1 PMC119947P1
UniSTS entry: Chr 1 WI-22175 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

NM_181359.2 Homo sapiens interleukin 6 receptor (IL6R), transcript variant 2, mRNA PA
NM_000565.3 Homo sapiens interleukin 6 receptor (IL6R), transcript variant 1, mRNA PA
BC089410.1 Homo sapiens interleukin 6 receptor, mRNA (cDNA clone MGC:104991 IMAGE:3078506), complete cds PA
AK223582.1 Homo sapiens mRNA for interleukin 6 receptor isoform 1 precursor variant, clone: FCC130B11 P
BC132686.1 Homo sapiens interleukin 6 receptor, mRNA (cDNA clone MGC:164317 IMAGE:40146708), complete cds P
BC132684.1 Homo sapiens interleukin 6 receptor, mRNA (cDNA clone MGC:164315 IMAGE:40146706), complete cds P
X12830.1 Human mRNA for interleukin-6 (IL-6) receptor P
AK293013.1 Homo sapiens cDNA FLJ75333 complete cds, highly similar to Homo sapiens interleukin 6 receptor (IL6R), transcript variant 2, mRNA P
AK312730.1 Homo sapiens cDNA, FLJ93136, highly similar to Homo sapiens interleukin 6 receptor (IL6R), mRNA P
X58298.1 Human mRNA for interleukin-6-receptor P
BC035327.1 Homo sapiens, clone IMAGE:5183790, mRNA PA
NM_001206866.1 Homo sapiens interleukin 6 receptor (IL6R), transcript variant 3, mRNA PA
S72848.1 sIL-6R=Soluble interleukin-6 receptor {alternatively spliced} [human, peripheral blood mononuclear cells (PBMC), mRNA Partial, 162 nt]

EST sequences (10 of 179) [Show all sequences]

AI003332.1 Clone IMAGE:1685300 brain 3' read
AI123326.1 Clone IMAGE:1689967 mixed 3' read
CB045797.1 Clone IMAGE:3218455 intestine 5' read
CB045796.1 Clone IMAGE:3218455 intestine 3' read A
R24966.1 Clone IMAGE:35084 brain 5' read
BX113990.1 Clone IMAGp998C131855_;_IMAGE:754500 mixed
R27940.1 Clone IMAGE:134646 placenta 5' read
CB162136.1 Clone L17N670205n1-17-G12 liver 5' read
CB163591.1 Clone L17N670205n1-25-B06 liver 5' read
CB164754.1 Clone L17N670205n1-13-B09 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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