> Disrupted in schizophrenia 1 (DISC1)
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UGID:133110     UniGene Hs.13318     Homo sapiens (human)   DISC1 Order cDNA clone, Links
Disrupted in schizophrenia 1 (DISC1)

Human protein-coding gene DISC1. Represented by 328 ESTs from 184 cDNA libraries. Corresponds to 32 reference sequences (different isoforms). [UniGene 133110 - Hs.13318]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001158009.1 DISC1 gene product H. sapiens 100.0 885
NP_001025275.1 tsnax gene product D. rerio 75.1 280
NP_001079762.1 translin-associated factor X X. laevis 74.5 293
NP_777279.2 Disc1 gene product M. musculus 60.9 851
Other hits (2 of 24) [Show all]SpeciesId(%)Len(aa)
NP_001230536.1 TSNAX gene product S. scrofa 98.3 289
XP_001151459.1 PREDICTED: disrupted in schizophrenia 1 protein isoform 1 P. troglodytes 98.0 857

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; pharynx; testis; placenta; connective tissue; heart; intestine; ovary; uncharacterized tissue; blood; liver; embryonic tissue; eye; umbilical cord; mixed; adrenal gland; mammary gland; uterus; kidney; lung; vascular; prostate; stomach; bladder; muscle; thyroid; mouth; esophagus; thymus; trachea; salivary gland; spinal cord; skin; pancreas; adipose tissue; spleen; ascites; bone marrow; ear; nerve; ganglia; bone
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q42.1
UniSTS entry: Chr 1 D1S2517
UniSTS entry: Chr 1 SHGC-58926
UniSTS entry: Chr 1 D1S2191 [Map Viewer]
UniSTS entry: Chr 1 D11S3316
UniSTS entry: Chr 1 RH121953
UniSTS entry: Chr 1 SHGC-76529 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (66)

AB007926.1 Homo sapiens mRNA for KIAA0457 protein, partial cds P
NM_005999.2 Homo sapiens translin-associated factor X (TSNAX), mRNA PA
AF222980.1 Homo sapiens disrupted in Schizophrenia 1 protein (DISC1) mRNA, complete cds PA
NM_001012959.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant S, mRNA PA
NM_001012958.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Es, mRNA P
NM_001012957.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant Lv, mRNA PA
AK025293.1 Homo sapiens cDNA: FLJ21640 fis, clone COL08304, highly similar to AF222980 Homo sapiens disrupted in Schizophrenia 1 protein (DISC1) mRNA PA
NM_018662.2 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant L, mRNA PA
BC010376.1 Homo sapiens translin-associated factor X, mRNA (cDNA clone MGC:13527 IMAGE:4283594), complete cds PA
BC011797.1 Homo sapiens translin-associated factor X, mRNA (cDNA clone MGC:19629 IMAGE:4138517), complete cds PA
BC142622.1 Homo sapiens cDNA clone IMAGE:40147457, containing frame-shift errors PA
BC151225.1 Homo sapiens disrupted in schizophrenia 1, mRNA (cDNA clone MGC:166810 IMAGE:9007180), complete cds PA
AK313068.1 Homo sapiens cDNA, FLJ93547, Homo sapiens translin-associated factor X (TSNAX), mRNA P
AK096457.1 Homo sapiens cDNA FLJ39138 fis, clone NTONG2009068 P
AF230316.1 Homo sapiens TRAX/DISC1 intergenic exon C
AF230315.1 Homo sapiens TRAX/DISC1 intergenic exon B
FJ804216.1 Homo sapiens disrupted in schizophrenia 1 isoform 46 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804215.1 Homo sapiens disrupted in schizophrenia 1 isoform 45 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804214.1 Homo sapiens disrupted in schizophrenia 1 isoform 44 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804213.1 Homo sapiens disrupted in schizophrenia 1 isoform 43 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804212.1 Homo sapiens disrupted in schizophrenia 1 isoform 42 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804211.1 Homo sapiens disrupted in schizophrenia 1 isoform 41 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804207.1 Homo sapiens disrupted in schizophrenia 1 isoform 37 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804205.1 Homo sapiens disrupted in schizophrenia 1 isoform 35 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804204.1 Homo sapiens disrupted in schizophrenia 1 isoform 34 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804202.1 Homo sapiens disrupted in schizophrenia 1 isoform 32 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804199.1 Homo sapiens disrupted in schizophrenia 1 isoform 29 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804196.1 Homo sapiens disrupted in schizophrenia 1 isoform 26 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804190.1 Homo sapiens disrupted in schizophrenia 1 isoform 19 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804187.1 Homo sapiens disrupted in schizophrenia 1 isoform 16 (DISC1) mRNA, complete cds, alternatively spliced P
FJ804186.1 Homo sapiens disrupted in schizophrenia 1 isoform 15 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804184.1 Homo sapiens disrupted in schizophrenia 1 isoform 13 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804181.1 Homo sapiens disrupted in schizophrenia 1 isoform 10 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804179.1 Homo sapiens disrupted in schizophrenia 1 isoform 8 (DISC1) mRNA, complete cds, alternatively spliced PA
FJ804177.1 Homo sapiens disrupted in schizophrenia 1 isoform 6 (DISC1) mRNA, complete cds, alternatively spliced PA
NM_001164549.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant l, mRNA P
NM_001164548.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant k, mRNA PA
NM_001164547.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant j, mRNA P
NM_001164546.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant i, mRNA P
NM_001164545.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant h, mRNA PA
NM_001164544.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant g, mRNA PA
NM_001164542.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant f, mRNA P
NM_001164541.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant e, mRNA P
NM_001164540.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant d, mRNA PA
NM_001164539.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant c, mRNA P
NM_001164538.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant b, mRNA P
NM_001164537.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant a, mRNA PA
NM_001164556.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant t, mRNA PA
NM_001164555.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant r, mRNA P
NM_001164554.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant q, mRNA P
NM_001164553.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant p, mRNA PA
NM_001164552.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant o, mRNA PA
NM_001164551.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant n, mRNA P
NM_001164550.1 Homo sapiens disrupted in schizophrenia 1 (DISC1), transcript variant m, mRNA PA
X95073.1 H.sapiens mRNA for translin associated protein X PA
NR_028398.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 6, non-coding RNA PA
NR_028400.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 8, non-coding RNA P
NR_028397.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 5, non-coding RNA PA
NR_028394.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 2, non-coding RNA PA
NR_028396.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 4, non-coding RNA PA
NR_028399.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 7, non-coding RNA P
NR_028395.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 3, non-coding RNA PA
NR_028393.1 Homo sapiens TSNAX-DISC1 readthrough (TSNAX-DISC1), transcript variant 1, non-coding RNA PA
AJ506178.1 Homo sapiens mRNA for disrupted in schizophrenia 1 (DISC1 gene), isoform E P
AJ506177.1 Homo sapiens mRNA for disrupted in schizophrenia 1 (DISC1 gene), short isoform P
BC038954.1 Homo sapiens cDNA clone IMAGE:5756143, containing frame-shift errors PA

EST sequences (10 of 328) [Show all sequences]

AA862725.1 Clone IMAGE:1469121 uncharacterized tissue 3' read A
AI075754.1 Clone IMAGE:1676892 embryonic tissue 3' read A
AI128808.1 Clone IMAGE:1694399 heart 3' read
AI139969.1 Clone IMAGE:1689878 mixed 3' read A
BX095963.1 Clone IMAGp998E226097_;_IMAGE:2451837 uterus A
BX106573.1 Clone IMAGp998H121817_;_IMAGE:740027 ovary
CB164660.1 Clone L17N670205n1-40-H10 liver 5' read
CB124764.1 Clone L4SNU368s1-2-D09 liver 5' read
CB133571.1 Clone L4SNU368s1-7-F05 liver 5' read
CB133257.1 Clone L4SNU368s1-18-F01 liver 5' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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