> Dihydrolipoamide dehydrogenase (DLD)
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UGID:149324     UniGene Hs.131711     Homo sapiens (human)   DLD Order cDNA clone, Links
Dihydrolipoamide dehydrogenase (DLD)

Human protein-coding gene DLD. Represented by 951 ESTs from 324 cDNA libraries. Corresponds to reference sequence NM_000108.3. [UniGene 149324 - Hs.131711]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001165051.2 PREDICTED: dihydrolipoyl dehydrogenase, mitochondrial isoform 4 P. troglodytes 100.0 537
NP_000099.2 DLD gene product H. sapiens 100.0 508
XP_003896521.1 PREDICTED: dihydrolipoyl dehydrogenase, mitochondrial P. anubis 99.8 508
XP_001095232.2 PREDICTED: dihydrolipoyl dehydrogenase, mitochondrial isoform 3 M. mulatta 99.6 485
NP_031887.2 dihydrolipoyl dehydrogenase, mitochondrial precursor M. musculus 96.7 508
NP_001080894.1 dihydrolipoamide dehydrogenase X. laevis 91.5 508
NP_958914.1 dldh gene product D. rerio 88.4 506
NP_502753.2 hypothetical protein LLC1.3 C. elegans 76.6 482
NP_649017.1 CG7430, isoform A D. melanogaster 74.4 499
NP_116635.1 dihydrolipoyl dehydrogenase S. cerevisiae 64.8 471
NP_175237.1 dihydrolipoyl dehydrogenase 1 A. thaliana 63.4 473
XP_959535.2 dihydrolipoyl dehydrogenase, mitochondrial precursor N. crassa 61.2 473
XP_001695163.1 dihydrolipoyl dehydrogenase C. reinhardtii 60.0 497
Other hits (2 of 57) [Show all]SpeciesId(%)Len(aa)
XP_001491626.1 PREDICTED: dihydrolipoyl dehydrogenase, mitochondrial isoform 1 E. caballus 99.4 508
NP_001003294.1 DLD gene product C. lupus familiaris 99.2 508

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; kidney; testis; uncharacterized tissue; lymph node; muscle; uterus; embryonic tissue; placenta; heart; umbilical cord; liver; bladder; intestine; ovary; skin; blood; connective tissue; adrenal gland; eye; trachea; parathyroid; lymph; tonsil; ascites; lung; thymus; prostate; pharynx; thyroid; nerve; epididymis; vascular; mammary gland; pancreas; esophagus; stomach; spinal cord; bone marrow; mouth; spleen; bone; salivary gland; cervix; larynx; pituitary gland; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q31-q32
UniSTS entry: RH130917
UniSTS entry: Chr 7 G54025
UniSTS entry: Chr 7 DLD
UniSTS entry: Chr 7 WIAF-2151
UniSTS entry: Chr 7 IB1079 [Map Viewer]
UniSTS entry: Chr 7 D7S2771 [Map Viewer]
UniSTS entry: Chr 7 RH102910
UniSTS entry: Chr 7 RH80342
UniSTS entry: Chr 7 RH103475
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (14)

NM_000108.3 Homo sapiens dihydrolipoamide dehydrogenase (DLD), nuclear gene encoding mitochondrial protein, mRNA P
AB209703.1 Homo sapiens mRNA for Dihydrolipoamide dehydrogenase, variant protein P
J03490.1 Human lipoamide dehydrogenase mRNA, complete cds P
AK225301.1 Homo sapiens mRNA for dihydrolipoamide dehydrogenase precursor variant, clone: HEP01396 P
AK225289.1 Homo sapiens mRNA for dihydrolipoamide dehydrogenase precursor variant, clone: HEP02468 P
BC018696.2 Homo sapiens dihydrolipoamide dehydrogenase, mRNA (cDNA clone MGC:3866 IMAGE:3029752), complete cds PA
BC018648.2 Homo sapiens dihydrolipoamide dehydrogenase, mRNA (cDNA clone MGC:2115 IMAGE:3029752), complete cds PA
AK310220.1 Homo sapiens cDNA, FLJ17262 P
AK312346.1 Homo sapiens cDNA, FLJ92665, highly similar to Homo sapiens dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) (DLD), mRNA P
AK294146.1 Homo sapiens cDNA FLJ56061 complete cds, highly similar to Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) P
AK300077.1 Homo sapiens cDNA FLJ50661 complete cds, highly similar to Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) P
AK297508.1 Homo sapiens cDNA FLJ56112 complete cds, highly similar to Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) P
AK295080.1 Homo sapiens cDNA FLJ50515 complete cds, highly similar to Dihydrolipoyl dehydrogenase, mitochondrial precursor (EC 1.8.1.4) P
J03620.1 Human dihydrolipoamide dehydrogenase mRNA, complete cds P

EST sequences (10 of 951) [Show all sequences]

AA863319.1 Clone IMAGE:1456790 kidney 3' read
AA834173.1 Clone IMAGE:1421115 kidney
AI023073.1 Clone IMAGE:1651726 skin 3' read
AI026997.1 Clone IMAGE:1649385 parathyroid 3' read A
AI027435.1 Clone IMAGE:1650189 parathyroid 3' read A
AI042304.1 Clone IMAGE:1665762 skin 3' read A
AI042643.1 Clone IMAGE:1668159 parathyroid 3' read A
AI082640.1 Clone IMAGE:1669884 brain 3' read A
AI090941.1 Clone IMAGE:1690376 mixed 3' read
AI093512.1 Clone IMAGE:1695676 uterus 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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