> Eukaryotic translation initiation factor 4A1 (EIF4A1)
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UGID:148528     UniGene Hs.129673     Homo sapiens (human)   EIF4A1 Order cDNA clone, Links
Eukaryotic translation initiation factor 4A1 (EIF4A1)

Human protein-coding gene EIF4A1. Represented by 5615 ESTs from 742 cDNA libraries. Corresponds to 4 reference sequences (different isoforms). [UniGene 148528 - Hs.129673]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_056485.2 SENP3 gene product H. sapiens 100.0 573
XP_003362496.1 PREDICTED: eukaryotic initiation factor 4A-I isoform 2 E. caballus 100.0 405
NP_001093666.1 EIF4A1 gene product S. scrofa 100.0 405
NP_001192057.1 sentrin-specific protease 3 P. troglodytes 99.8 573
XP_003912309.1 PREDICTED: sentrin-specific protease 3 P. anubis 99.7 971
XP_001110023.2 PREDICTED: sentrin-specific protease 3-like isoform 3 M. mulatta 99.6 970
NP_001086413.1 translation initiation factor eIF4A II X. laevis 98.5 405
NP_109627.3 Senp3 gene product M. musculus 95.2 567
NP_938180.1 eif4a1a gene product D. rerio 94.6 405
XP_958421.2 eIF4A N. crassa 84.9 396
NP_476595.1 eukaryotic initiation factor 4a, isoform C D. melanogaster 80.9 402
XP_001691452.1 eukaryotic initiation factor 4A-like protein C. reinhardtii 79.8 411
NP_001078148.1 translational initiation factor 4A-1 A. thaliana 79.3 400
NP_001022623.1 Protein INF-1, isoform a C. elegans 79.3 400
NP_012985.3 Tif1p S. cerevisiae 74.2 388
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
NP_001011139.1 eif4a1 gene product X. tropicalis 98.3 405
XP_001511956.2 PREDICTED: eukaryotic initiation factor 4A-I-like O. anatinus 97.8 401

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; embryonic tissue; testis; pancreas; skin; placenta; liver; uncharacterized tissue; uterus; intestine; prostate; eye; mammary gland; kidney; cervix; stomach; lymph; ascites; ovary; blood; bone; connective tissue; mixed; muscle; thymus; heart; bone marrow; vascular; spleen; lymph node; adrenal gland; salivary gland; thyroid; esophagus; bladder; larynx; tonsil; umbilical cord; pharynx; mouth; parathyroid; nerve; adipose tissue; trachea; pituitary gland; ganglia; epididymis; ear; amniotic fluid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 17
Map position: 17p13
UniSTS entry: Chr 17 RH47184
UniSTS entry: Chr 17 RH11592
UniSTS entry: Chr 17 RH11637
UniSTS entry: Chr 17 SHGC-31951
UniSTS entry: Chr 17 A005T43 [Map Viewer]
UniSTS entry: Chr 17 G66079
UniSTS entry: Chr 17 A004D02
UniSTS entry: Chr 13 D13S1550
UniSTS entry: Chr 17 RH36626
UniSTS entry: Chr 12 GDB:451634
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

AK130082.1 Homo sapiens cDNA FLJ26572 fis, clone LNF05779, highly similar to Eukaryotic initiation factor 4A-I (eIF-4A-I) P
NM_001416.3 Homo sapiens eukaryotic translation initiation factor 4A1 (EIF4A1), transcript variant 1, mRNA PA
BC073752.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone MGC:88756 IMAGE:6371531), complete cds PA
BT019881.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 mRNA, complete cds P
BT019880.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 mRNA, complete cds P
NR_002912.1 Homo sapiens small nucleolar RNA, H/ACA box 67 (SNORA67), small nucleolar RNA
BC006210.2 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone IMAGE:2821876), partial cds PA
BC009585.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone MGC:14648 IMAGE:4096621), complete cds PA
AK289453.1 Homo sapiens cDNA FLJ78614 complete cds, highly similar to Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA P
AK291971.1 Homo sapiens cDNA FLJ78244 complete cds, highly similar to Homo sapiens eukaryotic translation initiation factor 4A, isoform 1 (EIF4A1), mRNA P
AK312630.1 Homo sapiens cDNA, FLJ93014, Homo sapiens eukaryotic translation initiation factor 4A, isoform 1(EIF4A1), mRNA P
AK297916.1 Homo sapiens cDNA FLJ58596 complete cds, highly similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-) P
AK303599.1 Homo sapiens cDNA FLJ57766 complete cds, moderately similar to Eukaryotic initiation factor 4A-I (EC 3.6.1.-) P
BC032078.1 Homo sapiens eukaryotic translation initiation factor 4A, isoform 1, mRNA (cDNA clone IMAGE:3880019) PA
Y11161.1 H.sapiens U67 small nucleolar RNA gene
NM_001204510.1 Homo sapiens eukaryotic translation initiation factor 4A1 (EIF4A1), transcript variant 2, mRNA PA
NR_037926.1 Homo sapiens SENP3-EIF4A1 readthrough (SENP3-EIF4A1), non-coding RNA PA
D13748.1 Homo sapiens mRNA for eukaryotic initiation factor 4AI, complete cds P

EST sequences (10 of 5615) [Show all sequences]

AA961718.1 Clone IMAGE:1598349 uncharacterized tissue 3' read A
AA970221.1 Clone IMAGE:1575173 kidney 3' read
AA970752.1 Clone IMAGE:1576454 intestine 3' read A
AA970810.1 Clone IMAGE:1576512 intestine 3' read A
R14761.1 Clone IMAGE:30171 brain 5' read P
AA983521.1 Clone IMAGE:1598461 uncharacterized tissue 3' read A
AA983725.1 Clone IMAGE:1490873 skin 3' read A
AA993192.1 Clone IMAGE:1624319 embryonic tissue 3' read PA
AA886411.1 Clone IMAGE:1500673 kidney 3' read A
AI002526.1 Clone IMAGE:1594247 kidney 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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