Glutamate receptor, ionotropic, kainate 3 (GRIK3)

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UGID:148248 UniGene Hs.128848 Homo sapiens (human) GRIK3

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Glutamate receptor, ionotropic, kainate 3 (GRIK3)

Human protein-coding gene GRIK3. Represented by 55 ESTs from 34 cDNA libraries. Corresponds to reference sequence NM_000831.3. [UniGene 148248 - Hs.128848]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_000822.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	GRIK3 gene product	H. sapiens	100.0	918
XP_003891655.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: glutamate receptor, ionotropic kainate 3	P. anubis	99.9	918
XP_524666.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: glutamate receptor, ionotropic kainate 3 isoform 2	P. troglodytes	99.8	918
XP_001111351.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: glutamate receptor, ionotropic kainate 3-like isoform 2	M. mulatta	99.7	918
NP_001074566.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Grik3 gene product	M. musculus	99.3	918
XP_002664816.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: glutamate receptor, ionotropic kainate 3-like	D. rerio	81.2	883
NP_001153158.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	glutamate receptor, ionotropic, kainate 2	X. laevis	81.2	888
NP_492017.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Protein GLR-3	C. elegans	54.2	271
NP_650925.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CG3822	D. melanogaster	52.7	826
Other hits (2 of 33) [Show all]		Species	Id(%)	Len(aa)
XP_850331.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: LOW QUALITY PROTEIN: glutamate receptor, ionotropic kainate 3	C. lupus familiaris	99.2	918
NP_001192932.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	glutamate receptor, ionotropic kainate 3 precursor	B. taurus	99.2	918

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; eye; lung; connective tissue; ganglia; intestine; testis

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1p34.3
UniSTS entry:	Chr 1	D11S4066
UniSTS entry:	Chr 1	RH103118
UniSTS entry:	Chr 1	SHGC-74612	[Map Viewer]
UniSTS entry:	Chr 1	SHGC-31550	[Map Viewer]
UniSTS entry:	Chr 1	RH79120	[Map Viewer]
UniSTS entry:	Chr 1	GRIK3_966

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (4)

NM_000831.3	Homo sapiens glutamate receptor, ionotropic, kainate 3 (GRIK3), mRNA	PA
AJ299451.1	Homo sapiens mRNA for glutamate receptor 7 (GRIK3 gene)	P
AJ249210.1	Homo sapiens mRNA for glutamate/kainate receptor subtype GluR7 (GRIK3 gene)	PA
U16127.1	Human glutamate/kainate receptor subunit (EAA5) mRNA, complete cds	P

EST sequences (10 of 55) [Show all sequences]

R14775.1	Clone IMAGE:30182	brain	5' read
AA989064.1	Clone IMAGE:1602920	lung	3' read	A
R19589.1	Clone IMAGE:33457	brain	5' read
R20458.1	Clone IMAGE:34344	brain	5' read
BX101459.1	Clone IMAGp998F11280_;_IMAGE:49391	brain		A
AI339283.1	Clone IMAGE:1946299	uncharacterized tissue	3' read	A
AI361853.1	Clone IMAGE:2027898	uncharacterized tissue	3' read
R42545.1	Clone IMAGE:30182	brain	3' read	A
AI573286.1	Clone IMAGE:2166592	brain	3' read	P
AI650416.1	Clone IMAGE:2303468	uncharacterized tissue	3' read	A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria