> Actin, alpha 1, skeletal muscle (ACTA1)
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UGID:130964     UniGene Hs.1288     Homo sapiens (human)   ACTA1 Order cDNA clone, Links
Actin, alpha 1, skeletal muscle (ACTA1)

Human protein-coding gene ACTA1. Represented by 1054 ESTs from 123 cDNA libraries. Corresponds to reference sequence NM_001100.3. [UniGene 130964 - Hs.1288]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_033736.1 Acta1 gene product M. musculus 100.0 376
NP_062085.1 Acta1 gene product R. norvegicus 100.0 376
XP_003340224.1 PREDICTED: LOW QUALITY PROTEIN: actin, alpha skeletal muscle-like M. domestica 100.0 376
XP_003215863.1 PREDICTED: actin, alpha skeletal muscle-like isoform 1 A. carolinensis 100.0 376
NP_001188195.1 actin alpha sarcomeric/cardiac I. punctatus 100.0 376
NP_001079664.1 similar to actin alpha X. laevis 100.0 376
NP_001006709.1 acta1 gene product X. tropicalis 100.0 376
NP_001026234.1 ACTA1 gene product G. gallus 100.0 376
XP_002802173.1 PREDICTED: actin, alpha skeletal muscle-like isoform 2 M. mulatta 100.0 376
XP_003893841.1 PREDICTED: actin, alpha skeletal muscle P. anubis 100.0 376
XP_003308856.1 PREDICTED: actin, alpha skeletal muscle P. troglodytes 100.0 376
NP_001091.1 ACTA1 gene product H. sapiens 100.0 376
XP_001497763.1 PREDICTED: actin, alpha skeletal muscle isoform 1 E. caballus 100.0 376
NP_001161267.1 ACTA1 gene product S. scrofa 100.0 376
NP_776650.1 ACTA1 gene product B. taurus 100.0 376
XP_004021390.1 PREDICTED: actin, alpha skeletal muscle isoform 1 O. aries 100.0 376
XP_002722940.1 PREDICTED: cytoplasmic beta-actin O. cuniculus 100.0 376
XP_003962484.1 PREDICTED: actin, alpha cardiac-like isoform 1 T. rubripes 99.7 376
NP_001142321.1 uncharacterized protein LOC100274491 Z. mays 99.7 376
XP_002200536.1 PREDICTED: actin, alpha cardiac muscle 1 T. guttata 99.7 376
NP_001002066.1 zgc:86709 gene product D. rerio 99.7 376
NP_001117011.1 fast myotomal muscle actin S. salar 99.7 376
XP_004065536.1 PREDICTED: actin, alpha cardiac-like isoform 1 O. latipes 99.7 376
XP_003442991.1 PREDICTED: actin, alpha cardiac muscle 1-like isoform 1 O. niloticus 99.7 376
XP_003206599.1 PREDICTED: actin, alpha cardiac muscle 1 M. gallopavo 99.7 376
XP_535424.1 PREDICTED: actin, alpha cardiac muscle 1 isoform 3 C. lupus familiaris 99.7 376
NP_508841.1 Protein ACT-4, isoform a C. elegans 96.3 375
NP_511052.1 actin 5C, isoform B D. melanogaster 96.3 375
XP_001699068.1 actin C. reinhardtii 93.6 376
NP_187818.1 actin-11 A. thaliana 91.8 376
NP_116614.1 actin S. cerevisiae 90.6 373
XP_961133.2 actin N. crassa 90.1 373
Other hits (2 of 46) [Show all]SpeciesId(%)Len(aa)
XP_002132052.1 PREDICTED: similar to CsMA-1 isoform 2 C. intestinalis 99.2 376
XP_001507188.1 PREDICTED: actin, alpha skeletal muscle-like isoform 1 O. anatinus 98.1 376

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: muscle; heart; larynx; thyroid; lung; ovary; tonsil; brain; eye; bone; epididymis; adrenal gland; bladder; adipose tissue; nerve; umbilical cord; peritoneum; prostate; uncharacterized tissue; pituitary gland; embryonic tissue; mixed; intestine; liver; pancreas; kidney; vascular; pharynx; placenta; mouth; uterus; mammary gland; testis; bone marrow
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 1
Map position: 1q42.13
UniSTS entry: Chr 1 RH36158
UniSTS entry: Chr 3 LOC345651
UniSTS entry: Chr 15 PMC350549P3
UniSTS entry: Chr 15 PMC151001P2
UniSTS entry: Chr 15 PMC23952P1
UniSTS entry: Chr 6 Acta1
UniSTS entry: Chr 1 aa658676
UniSTS entry: Chr 11 G49387
UniSTS entry: Chr 15 G15871
UniSTS entry: Chr 1 PMC110143P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AY280960.1 Homo sapiens actin alpha 1 skeletal muscle protein (ACTA1) mRNA, complete cds; alternatively spliced P
BX648545.1 Homo sapiens mRNA; cDNA DKFZp779F0855 (from clone DKFZp779F0855) PA
NM_001100.3 Homo sapiens actin, alpha 1, skeletal muscle (ACTA1), mRNA PA
J00068.1 Human adult skeletal muscle alpha-actin mRNA P
CR536516.1 Homo sapiens full open reading frame cDNA clone RZPDo834D1020D for gene ACTA1, actin, alpha 1, skeletal muscle; complete cds, incl. stopcodon P
CR541796.1 Homo sapiens full open reading frame cDNA clone RZPDo834B0631D for gene ACTA1, actin, alpha 1, skeletal muscle; complete cds, without stopcodon P
BC012597.1 Homo sapiens actin, alpha 1, skeletal muscle, mRNA (cDNA clone MGC:13546 IMAGE:4291656), complete cds PA
AK096902.1 Homo sapiens cDNA FLJ39583 fis, clone SKMUS2004897, highly similar to ACTIN, ALPHA SKELETAL MUSCLE P
AK300697.1 Homo sapiens cDNA FLJ53662 complete cds, highly similar to Actin, alpha skeletal muscle PA

EST sequences (10 of 1054) [Show all sequences]

AA866018.1 Clone IMAGE:1459357 kidney 3' read A
AA970272.1 Clone IMAGE:1575199 kidney 3' read A
AA974659.1 Clone IMAGE:1574449 kidney 3' read A
AI092804.1 Clone IMAGE:1693105 heart 3' read A
AI093052.1 Clone IMAGE:1694632 heart 3' read A
AI140645.1 Clone IMAGE:1739693 lung 3' read
AI141546.1 Clone IMAGE:1694028 heart 3' read PA
R24091.1 Clone IMAGE:131505 placenta 5' read
BX116897.1 Clone IMAGp998K19670_;_IMAGE:299658 lung P
AI193510.1 Clone IMAGE:1744304 lung 3' read PA


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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