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Actin, alpha 1, skeletal muscle (ACTA1)
Human protein-coding gene ACTA1. Represented by 1054 ESTs from 123 cDNA libraries. Corresponds to reference sequence NM_001100.3. [UniGene 130964 - Hs.1288]
SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
| Best Hits and Hits from model organisms | Species | Id(%) | Len(aa) |
|
|
Acta1 gene product |
M. musculus |
100.0 |
376 |
|
|
Acta1 gene product |
R. norvegicus |
100.0 |
376 |
|
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PREDICTED: LOW QUALITY PROTEIN: actin, alpha skeletal muscle-like |
M. domestica |
100.0 |
376 |
|
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PREDICTED: actin, alpha skeletal muscle-like isoform 1 |
A. carolinensis |
100.0 |
376 |
|
|
actin alpha sarcomeric/cardiac |
I. punctatus |
100.0 |
376 |
|
|
similar to actin alpha |
X. laevis |
100.0 |
376 |
|
|
acta1 gene product |
X. tropicalis |
100.0 |
376 |
|
|
ACTA1 gene product |
G. gallus |
100.0 |
376 |
|
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PREDICTED: actin, alpha skeletal muscle-like isoform 2 |
M. mulatta |
100.0 |
376 |
|
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PREDICTED: actin, alpha skeletal muscle |
P. anubis |
100.0 |
376 |
|
|
PREDICTED: actin, alpha skeletal muscle |
P. troglodytes |
100.0 |
376 |
|
|
ACTA1 gene product |
H. sapiens |
100.0 |
376 |
|
|
PREDICTED: actin, alpha skeletal muscle isoform 1 |
E. caballus |
100.0 |
376 |
|
|
ACTA1 gene product |
S. scrofa |
100.0 |
376 |
|
|
ACTA1 gene product |
B. taurus |
100.0 |
376 |
|
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PREDICTED: actin, alpha skeletal muscle isoform 1 |
O. aries |
100.0 |
376 |
|
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PREDICTED: cytoplasmic beta-actin |
O. cuniculus |
100.0 |
376 |
|
|
PREDICTED: actin, alpha cardiac-like isoform 1 |
T. rubripes |
99.7 |
376 |
|
|
uncharacterized protein LOC100274491 |
Z. mays |
99.7 |
376 |
|
|
PREDICTED: actin, alpha cardiac muscle 1 |
T. guttata |
99.7 |
376 |
|
|
zgc:86709 gene product |
D. rerio |
99.7 |
376 |
|
|
fast myotomal muscle actin |
S. salar |
99.7 |
376 |
|
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PREDICTED: actin, alpha cardiac-like isoform 1 |
O. latipes |
99.7 |
376 |
|
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PREDICTED: actin, alpha cardiac muscle 1-like isoform 1 |
O. niloticus |
99.7 |
376 |
|
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PREDICTED: actin, alpha cardiac muscle 1 |
M. gallopavo |
99.7 |
376 |
|
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PREDICTED: actin, alpha cardiac muscle 1 isoform 3 |
C. lupus familiaris |
99.7 |
376 |
|
|
Protein ACT-4, isoform a |
C. elegans |
96.3 |
375 |
|
|
actin 5C, isoform B |
D. melanogaster |
96.3 |
375 |
|
|
actin |
C. reinhardtii |
93.6 |
376 |
|
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actin-11 |
A. thaliana |
91.8 |
376 |
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actin |
S. cerevisiae |
90.6 |
373 |
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actin |
N. crassa |
90.1 |
373 |
| Other hits (2 of 46) [Show all] | Species | Id(%) | Len(aa) |
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PREDICTED: similar to CsMA-1 isoform 2 |
C. intestinalis |
99.2 |
376 |
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PREDICTED: actin, alpha skeletal muscle-like isoform 1 |
O. anatinus |
98.1 |
376 |
GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
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EST Profile: | Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this] |
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GEO Profiles: |
Experimental gene expression data (Gene Expression Omnibus). |
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cDNA Sources: |
muscle; heart; larynx; thyroid; lung; ovary; tonsil; brain; eye; bone; epididymis; adrenal gland; bladder; adipose tissue; nerve; umbilical cord; peritoneum; prostate; uncharacterized tissue; pituitary gland; embryonic tissue; mixed; intestine; liver; pancreas; kidney; vascular; pharynx; placenta; mouth; uterus; mammary gland; testis; bone marrow |
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.
mRNA sequences (9)
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AY280960.1 |
Homo sapiens actin alpha 1 skeletal muscle protein (ACTA1) mRNA, complete cds; alternatively spliced |
P |
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BX648545.1 |
Homo sapiens mRNA; cDNA DKFZp779F0855 (from clone DKFZp779F0855) |
PA |
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NM_001100.3 |
Homo sapiens actin, alpha 1, skeletal muscle (ACTA1), mRNA |
PA |
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J00068.1 |
Human adult skeletal muscle alpha-actin mRNA |
P |
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CR536516.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834D1020D for gene ACTA1, actin, alpha 1, skeletal muscle; complete cds, incl. stopcodon |
P |
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CR541796.1 |
Homo sapiens full open reading frame cDNA clone RZPDo834B0631D for gene ACTA1, actin, alpha 1, skeletal muscle; complete cds, without stopcodon |
P |
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BC012597.1 |
Homo sapiens actin, alpha 1, skeletal muscle, mRNA (cDNA clone MGC:13546 IMAGE:4291656), complete cds |
PA |
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AK096902.1 |
Homo sapiens cDNA FLJ39583 fis, clone SKMUS2004897, highly similar to ACTIN, ALPHA SKELETAL MUSCLE |
P |
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AK300697.1 |
Homo sapiens cDNA FLJ53662 complete cds, highly similar to Actin, alpha skeletal muscle |
PA |
EST sequences (10 of 1054) [Show all sequences]
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AA866018.1 |
Clone IMAGE:1459357 |
kidney |
3' read |
A |
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AA970272.1 |
Clone IMAGE:1575199 |
kidney |
3' read |
A |
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AA974659.1 |
Clone IMAGE:1574449 |
kidney |
3' read |
A |
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AI092804.1 |
Clone IMAGE:1693105 |
heart |
3' read |
A |
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AI093052.1 |
Clone IMAGE:1694632 |
heart |
3' read |
A |
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AI140645.1 |
Clone IMAGE:1739693 |
lung |
3' read |
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AI141546.1 |
Clone IMAGE:1694028 |
heart |
3' read |
PA |
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R24091.1 |
Clone IMAGE:131505 |
placenta |
5' read |
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BX116897.1 |
Clone IMAGp998K19670_;_IMAGE:299658 |
lung |
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P |
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AI193510.1 |
Clone IMAGE:1744304 |
lung |
3' read |
PA |
Key to Symbols
P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria
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