> Vacuolar protein sorting 4 homolog B (S. cerevisiae) (VPS4B)
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UGID:147401     UniGene Hs.126550     Homo sapiens (human)   VPS4B Order cDNA clone, Links
Vacuolar protein sorting 4 homolog B (S. cerevisiae) (VPS4B)

Human protein-coding gene VPS4B. Represented by 297 ESTs from 166 cDNA libraries. Corresponds to reference sequence NM_004869.3. [UniGene 147401 - Hs.126550]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_523954.2 PREDICTED: vacuolar protein sorting-associated protein 4B isoform 2 P. troglodytes 100.0 443
NP_004860.2 VPS4B gene product H. sapiens 100.0 443
XP_002801004.1 PREDICTED: vacuolar protein sorting-associated protein 4B-like M. mulatta 99.8 443
XP_003914504.1 PREDICTED: vacuolar protein sorting-associated protein 4B P. anubis 99.8 443
NP_033216.2 Vps4b gene product M. musculus 97.8 443
NP_001080109.1 vacuolar protein sorting 4 homolog B X. laevis 93.4 441
NP_001094432.1 vacuolar protein sorting 4 homolog b-like D. rerio 91.5 435
NP_573258.1 vacuolar protein sorting 4 D. melanogaster 82.3 435
NP_490816.4 Protein VPS-4 C. elegans 79.8 425
XP_958048.1 vacuolar protein sorting-associated protein VPS4 N. crassa 74.3 439
NP_015499.1 AAA family ATPase VPS4 S. cerevisiae 73.8 435
XP_001701670.1 AAA-ATPase of VPS4/SKD1 family C. reinhardtii 71.6 426
NP_180328.1 vacuolar protein-sorting-associated protein 4 A. thaliana 69.5 428
Other hits (2 of 62) [Show all]SpeciesId(%)Len(aa)
XP_001490740.1 PREDICTED: vacuolar protein sorting-associated protein 4B-like E. caballus 98.4 443
NP_001069624.1 VPS4B gene product B. taurus 98.4 443

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; blood; adrenal gland; mammary gland; eye; pharynx; mixed; pancreas; salivary gland; mouth; thyroid; uncharacterized tissue; placenta; uterus; liver; prostate; lung; intestine; embryonic tissue; kidney; spleen; skin; ear; pituitary gland; bone marrow; connective tissue; vascular; ovary; muscle; bone; heart; trachea; esophagus; thymus; cervix; lymph; parathyroid; ascites; nerve; lymph node; bladder; stomach
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 18
Map position: 18q21.33
UniSTS entry: Chr 18 RH99091
UniSTS entry: Chr 18 D18S934E
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

NM_004869.3 Homo sapiens vacuolar protein sorting 4 homolog B (S. cerevisiae) (VPS4B), mRNA PA
AY232629.1 Homo sapiens cell migration-inducing 1 mRNA, complete cds P
AF195514.1 Homo sapiens VPS4-2 ATPase (VPS42) mRNA, complete cds PA
AK291253.1 Homo sapiens cDNA FLJ75934 complete cds, highly similar to Homo sapiens vacuolar protein sorting 4B (yeast) (VPS4B), mRNA P
AK290932.1 Homo sapiens cDNA FLJ78528 complete cds, highly similar to Homo sapiens vacuolar protein sorting 4B (yeast) (VPS4B), mRNA P
AK308892.1 Homo sapiens cDNA, FLJ98933 P
AK311041.1 Homo sapiens cDNA, FLJ18083 P
AK309322.1 Homo sapiens cDNA, FLJ99363 P
BC009692.2 Homo sapiens vacuolar protein sorting 4 homolog B (S. cerevisiae), mRNA (cDNA clone IMAGE:3892403), partial cds PA
AF038960.1 Homo sapiens SKD1 homolog mRNA, complete cds PA
BC039574.1 Homo sapiens vacuolar protein sorting 4 homolog B (S. cerevisiae), mRNA (cDNA clone MGC:48692 IMAGE:6042862), complete cds PA

EST sequences (10 of 297) [Show all sequences]

AA973716.1 Clone IMAGE:1586000 uncharacterized tissue 3' read
AA975929.1 Clone IMAGE:1568000 lung 3' read
AA906302.1 Clone IMAGE:1506756 mixed 3' read
AI093788.1 Clone IMAGE:1688443 mixed 3' read
CB051664.1 Clone IMAGE:3289711 uncharacterized tissue 3' read A
AI147133.1 Clone IMAGE:1509705 mixed 3' read A
BX116546.1 Clone IMAGp998B05122_;_IMAGE:124708 mixed P
AI208451.1 Clone IMAGE:1837266 testis 3' read A
CB116377.1 Clone L10ChoCK0-5-G11 liver 5' read
AI351034.1 Clone IMAGE:1934635 embryonic tissue 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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