> Interleukin 1, beta (IL1B)
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UGID:147310     UniGene Hs.126256     Homo sapiens (human)   IL1B Order cDNA clone, Links
Interleukin 1, beta (IL1B)

Human protein-coding gene IL1B. Represented by 489 ESTs from 71 cDNA libraries. EST representation biased toward vascular; infant. Corresponds to reference sequence NM_000576.2. [UniGene 147310 - Hs.126256]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_000567.1 IL1B gene product H. sapiens 100.0 268
XP_001147075.1 PREDICTED: interleukin-1 beta isoform 3 P. troglodytes 99.6 268
NP_032387.1 Il1b gene product M. musculus 76.6 268
Other hits (2 of 10) [Show all]SpeciesId(%)Len(aa)
NP_001036221.1 IL1B gene product M. mulatta 94.8 268
XP_003909194.1 PREDICTED: interleukin-1 beta P. anubis 94.0 267

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: vascular [show more like this]
infant [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: vascular; uncharacterized tissue; lung; blood; liver; connective tissue; brain; testis; skin; esophagus; stomach; muscle; eye; pancreas; bladder; uterus; mixed; intestine; spleen; bone marrow; pharynx; mouth
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q14
UniSTS entry: Chr 2 RH48318 [Map Viewer]
UniSTS entry: Chr 2 RH11481 [Map Viewer]
UniSTS entry: Chr 2 D2S2849 [Map Viewer]
UniSTS entry: Chr 2 PMC305895P1
UniSTS entry: Chr 2 G10509
UniSTS entry: Chr 2 IL1B_353
UniSTS entry: Chr 2 G60262
UniSTS entry: Chr 2 PMC317379P1
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

K02770.1 Human monocyte interleukin 1 (IL-1) mRNA, complete cds P
BT007213.1 Homo sapiens interleukin 1, beta mRNA, complete cds P
CR407679.1 Homo sapiens full open reading frame cDNA clone RZPDo834C113D for gene IL1B, interleukin 1, beta complete cds, without stopcodon P
M15330.1 Human interleukin 1-beta (IL1B) mRNA, complete cds P
M54933.1 Homo sapiens interleukin 1 precursor (IL1A) mRNA, complete cds P
NM_000576.2 Homo sapiens interleukin 1, beta (IL1B), mRNA P
BC008678.1 Homo sapiens interleukin 1, beta, mRNA (cDNA clone MGC:9216 IMAGE:3875593), complete cds PA
X02532.1 Human mRNA for interleukin 1 beta. Peripheral blood mononuclear cells P
AK313983.1 Homo sapiens cDNA, FLJ94633 P
AB451494.1 Homo sapiens IL1B mRNA for interleukin-1 beta precursor, partial cds, clone: FLJ80228DABN P
X56087.1 Human mRNA for prointerleukin 1 beta P
AF043335.1 Homo sapiens interleukin 1 beta (IL1b) mRNA, partial cds P

EST sequences (10 of 489) [Show all sequences]

AI022364.1 Clone IMAGE:1651640 skin 3' read
BX108825.1 Clone IMAGp998M08735 skin 5' read P
CB106295.1 Clone L3SNU475-1-F07 liver 5' read P
CB111028.1 Clone L5HLK1-9-F11 liver 5' read P
CB136640.1 Clone L5HLK1-41-D10 liver 5' read P
CB137586.1 Clone L5HLK1-35-E03 liver 5' read P
CB146078.1 Clone B2N807043-3-B03 brain 5' read P
CB154775.1 Clone B2N807043-24-F03 brain 5' read P
CB129835.1 Clone L15CKK1-2-C01 liver 5' read P
CB149561.1 Clone L15CKK1-46-E11 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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