DENN/MADD domain containing 1B (DENND1B)

Restricted Expression:

embryoid body [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

placenta; pharynx; pancreas; stomach; embryonic tissue; uncharacterized tissue; bone marrow; lymph node; intestine; liver; thymus; mouth; blood; prostate; connective tissue; kidney; vascular; mammary gland; ovary; testis; lung

NCBI

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Finding cDNAs

UGID:146909 UniGene Hs.125056 Homo sapiens (human) DENND1B

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DENN/MADD domain containing 1B (DENND1B)

Human protein-coding gene DENND1B. Represented by 50 ESTs from 33 cDNA libraries. EST representation biased toward embryoid body. [UniGene 146909 - Hs.125056]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001182144.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	DENND1B gene product	H. sapiens	99.8	402
XP_001138488.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: DENN domain-containing protein 1B isoform 4	P. troglodytes	99.5	402
NP_851992.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Dennd1b gene product	M. musculus	81.9	413
Other hits (2 of 16) [Show all]		Species	Id(%)	Len(aa)
XP_003893403.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: DENN domain-containing protein 1B	P. anubis	97.3	402
XP_002802047.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: DENN domain-containing protein 1B-like	M. mulatta	96.9	385

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	1
Map position:	1q31.3
UniSTS entry:	Chr 1	SHGC-76078	[Map Viewer]

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	BC074735.2	Homo sapiens DENN/MADD domain containing 1B, mRNA (cDNA clone IMAGE:30915191), complete cds	P
	AK024832.1	Homo sapiens cDNA: FLJ21179 fis, clone CAS11174	PA

EST sequences (10 of 50) [Show all sequences]

BX091956.1	Clone IMAGp998F16225_;_IMAGE:147855	placenta		P
AA824385.1	Clone 1391718	testis	3' read	PA
AI636062.1	Clone IMAGE:2296035	kidney	3' read
CB962211.1	Clone IMAGE:30319192	vascular	5' read
AI948992.1	Clone IMAGE:2471587	kidney	3' read
CD687414.1		pharynx
AW337298.1	Clone IMAGE:2834604	pancreas	3' read	A
R81505.1	Clone IMAGE:147855	placenta	3' read
R81750.1	Clone IMAGE:147855	placenta	5' read	P
AW865598.1		stomach

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria