> Hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (HCN2)
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UGID:146678     UniGene Hs.124161     Homo sapiens (human)   HCN2 Links
Hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (HCN2)

Human protein-coding gene HCN2. Represented by 38 ESTs from 21 cDNA libraries. EST representation biased toward adult. Corresponds to reference sequence NM_001194.3. [UniGene 146678 - Hs.124161]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001185.3 HCN2 gene product H. sapiens 100.0 888
NP_032252.1 Hcn2 gene product M. musculus 96.9 862
XP_685414.2 PREDICTED: hyperpolarization activated cyclic nucleotide-gated potassium channel 2 D. rerio 86.8 894
NP_001033946.2 I[[h]] channel, isoform I D. melanogaster 67.2 528
Other hits (2 of 38) [Show all]SpeciesId(%)Len(aa)
XP_004009512.1 PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, partial O. aries 99.1 750
NP_446136.1 Hcn2 gene product R. norvegicus 96.9 862

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
Restricted Expression: adult [show more like this]
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; mixed; pancreas; uncharacterized tissue; embryonic tissue; skin; cervix; eye; mammary gland; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19p13.3
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (6)

AF065164.2 Homo sapiens hyperpolarization-activated, cyclic nucleotide-gated channel 2 (HCN2) mRNA, complete cds P
AJ012582.1 Homo sapiens mRNA for hyperpolarization-activated cation channel HCN2 PA
NM_001194.3 Homo sapiens hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (HCN2), mRNA PA
DQ854815.1 Homo sapiens hyperpolarization-activated cyclic nucleotide-gated potassium channel 2 mRNA, partial cds P
AF064877.1 Homo sapiens ion channel BCNG-2 mRNA, partial cds P
BC039619.1 Homo sapiens hyperpolarization activated cyclic nucleotide-gated potassium channel 2, mRNA (cDNA clone IMAGE:5730201) P

EST sequences (10 of 38) [Show all sequences]

CB054837.1 Clone IMAGE:3291729 brain 3' read P
CB054838.1 Clone IMAGE:3291729 brain 5' read P
AI421964.1 Clone IMAGE:2098650 brain 3' read A
AI422949.1 Clone IMAGE:2097008 brain 3' read P
AI809833.1 Clone IMAGE:2386806 uncharacterized tissue 3' read P
BX281160.1 Clone IMAGp998M13329_;_IMAGE:179124 brain
BX282916.1 Clone IMAGp998O22642_;_IMAGE:289005 brain
AW073171.1 Clone IMAGE:2556243 brain 3' read P
AW452312.1 Clone IMAGE:3068387 uncharacterized tissue 3' read P
CK902965.1 Clone IMAGE:6546404 pancreas 3' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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