> Lysine (K)-specific demethylase 2A (KDM2A)
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UGID:146673     UniGene Hs.124147     Homo sapiens (human)   KDM2A
Lysine (K)-specific demethylase 2A (KDM2A)

Human protein-coding gene KDM2A. Represented by 515 ESTs from 260 cDNA libraries. Corresponds to 3 reference sequences (different isoforms). [UniGene 146673 - Hs.124147]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001172828.1 PREDICTED: lysine-specific demethylase 2A isoform 6 P. troglodytes 100.0 1161
NP_036440.1 KDM2A gene product H. sapiens 100.0 1161
XP_001107511.1 PREDICTED: lysine-specific demethylase 2A-like M. mulatta 99.9 1161
XP_003909537.1 PREDICTED: lysine-specific demethylase 2A isoform 1 P. anubis 99.9 1161
XP_865102.2 PREDICTED: lysine-specific demethylase 2A isoform 4 C. lupus familiaris 99.8 1161
XP_001497145.1 PREDICTED: lysine-specific demethylase 2A isoform 1 E. caballus 99.8 1161
XP_591785.4 PREDICTED: lysine-specific demethylase 2A isoform 1 B. taurus 99.8 1161
XP_002709273.1 PREDICTED: F-box and leucine-rich repeat protein 11-like O. cuniculus 99.8 1146
NP_001153562.1 KDM2A gene product S. scrofa 99.7 1161
NP_001001984.2 Kdm2a gene product M. musculus 98.9 1160
NP_001085840.1 lysine-specific demethylase 2B X. laevis 69.3 1251
XP_001339797.2 PREDICTED: lysine-specific demethylase 2A D. rerio 65.3 1249
NP_649864.2 lysine (K)-specific demethylase 2, isoform B D. melanogaster 59.3 1221
NP_498419.2 Protein JHDM-1, isoform b C. elegans 51.8 220
Other hits (2 of 31) [Show all]SpeciesId(%)Len(aa)
XP_004019970.1 PREDICTED: LOW QUALITY PROTEIN: lysine-specific demethylase 2A O. aries 99.5 1156
NP_001101985.1 lysine-specific demethylase 2A R. norvegicus 99.1 1160

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: mixed; brain; uncharacterized tissue; eye; uterus; connective tissue; thymus; pharynx; larynx; blood; testis; embryonic tissue; lung; pancreas; placenta; lymph node; ascites; kidney; stomach; mammary gland; liver; thyroid; intestine; skin; ovary; heart; adrenal gland; nerve; tonsil; bladder; lymph; cervix; spinal cord; bone; prostate; mouth; esophagus; pituitary gland; amniotic fluid; spleen; muscle; salivary gland; vascular; parathyroid; umbilical cord; epididymis
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 11
Map position: 11q13.2
UniSTS entry: Chr 11 STS-Z40471
UniSTS entry: Chr 11 RH18199
UniSTS entry: Chr 11 RH12099
UniSTS entry: Chr 11 RH124989
UniSTS entry: Chr 11 MARC_17215-17216:1023895331:5
UniSTS entry: Chr 11 FBXL11
UniSTS entry: Chr 1 D1S1425
UniSTS entry: Chr 1 D10S16
UniSTS entry: Chr 1 GDB:434012
UniSTS entry: Chr 1 D15S1477
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (18)

BC047486.1 Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA clone MGC:51265 IMAGE:5296445), complete cds PA
BC047371.1 Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA clone MGC:48461 IMAGE:5270744), complete cds PA
AB023221.2 Homo sapiens mRNA for KIAA1004 protein, partial cds P
AL117517.1 Homo sapiens mRNA; cDNA DKFZp434M1735 (from clone DKFZp434M1735) A
AK128293.1 Homo sapiens cDNA FLJ46431 fis, clone THYMU3014620, highly similar to Homo sapiens F-box protein Lilina (LILINA) mRNA P
BC056905.1 Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA clone IMAGE:6171996), partial cds PA
BC064360.1 Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA clone MGC:74784 IMAGE:5534384), complete cds PA
AF179221.1 Homo sapiens F-box protein Lilina (LILINA) mRNA, complete cds P
AK022684.1 Homo sapiens cDNA FLJ12622 fis, clone NT2RM4001731, highly similar to Homo sapiens F-box protein Lilina (LILINA) mRNA P
AK024505.1 Homo sapiens mRNA for FLJ00115 protein, partial cds P
BC001203.1 Homo sapiens, Similar to f-box and leucine-rich repeat protein 11, clone IMAGE:3357072, mRNA, partial cds PA
NM_012308.2 Homo sapiens lysine (K)-specific demethylase 2A (KDM2A), transcript variant 1, mRNA PA
AK096194.1 Homo sapiens cDNA FLJ38875 fis, clone MESAN2013936
AK299725.1 Homo sapiens cDNA FLJ51294 complete cds, highly similar to JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) P
BC027467.1 Homo sapiens F-box and leucine-rich repeat protein 11, mRNA (cDNA clone IMAGE:4478268), with apparent retained intron PA
AB490246.1 Homo sapiens kdm2a mRNA for SF-KDM2A, complete cds PA
NM_001256405.1 Homo sapiens lysine (K)-specific demethylase 2A (KDM2A), transcript variant 3, mRNA PA
NR_027473.1 Homo sapiens lysine (K)-specific demethylase 2A (KDM2A), transcript variant 2, non-coding RNA PA

EST sequences (10 of 515) [Show all sequences]

AA972523.1 Clone IMAGE:1435482 intestine 3' read
AA974213.1 Clone IMAGE:1586756 uncharacterized tissue 3' read A
AA991560.1 Clone IMAGE:1609701 mammary gland 3' read A
AI015261.1 Clone IMAGE:1641203 testis 3' read
AI032934.1 Clone IMAGE:1655291 mixed 3' read
AI076846.1 Clone IMAGE:1674071 mixed 3' read A
AI093127.1 Clone IMAGE:1694705 heart 3' read
AI093421.1 Clone IMAGE:1695235 uterus 3' read
AI141493.1 Clone IMAGE:1691876 heart 3' read A
T06467.1 Clone HFBDT87 brain


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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