TDP-glucose 4,6-dehydratase (TGDS)

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UGID:132907 UniGene Hs.12393 Homo sapiens (human) TGDS

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TDP-glucose 4,6-dehydratase (TGDS)

Human protein-coding gene TGDS. Represented by 172 ESTs from 92 cDNA libraries. Corresponds to reference sequence NM_014305.2. [UniGene 132907 - Hs.12393]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_055120.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TGDS gene product	H. sapiens	100.0	349
XP_001083495.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: dTDP-D-glucose 4,6-dehydratase	M. mulatta	99.7	349
XP_003914040.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: dTDP-D-glucose 4,6-dehydratase	P. anubis	99.7	349
NP_083854.3 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	Tgds gene product	M. musculus	93.2	354
NP_001088301.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	TDP-glucose 4,6-dehydratase	X. laevis	77.0	347
NP_956111.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	tgds gene product	D. rerio	66.2	266
XP_001701714.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	NAD-dependent epimerase/dehydratase	C. reinhardtii	54.0	310
XP_957289.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	hypothetical protein NCU00403	N. crassa	53.2	284
NP_188097.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	UDP-glucose 4,6-dehydratase	A. thaliana	51.4	331
Other hits (2 of 34) [Show all]		Species	Id(%)	Len(aa)
XP_522697.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: dTDP-D-glucose 4,6-dehydratase	P. troglodytes	99.1	349
XP_001491790.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: dTDP-D-glucose 4,6-dehydratase-like	E. caballus	98.6	354

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	GEO Profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	brain; uncharacterized tissue; mixed; lung; lymph node; umbilical cord; esophagus; bladder; amniotic fluid; liver; testis; uterus; placenta; prostate; intestine; embryonic tissue; skin; pituitary gland; bone marrow; ovary; pancreas; kidney; eye; blood; heart; stomach; thymus; ascites; muscle; mammary gland; bone; pharynx

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	13
Map position:	13q32.1
UniSTS entry:	Chr 13	RH102327

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (9)

AJ006068.1	Homo sapiens mRNA for dTDP-D-glucose 4,6-dehydratase	PA
NM_014305.2	Homo sapiens TDP-glucose 4,6-dehydratase (TGDS), mRNA	PA
AF048686.1	Homo sapiens dTDP-glucose 4,6-dehydratase like protein mRNA, complete cds	P
AY544125.1	Homo sapiens growth-inhibiting protein 21 mRNA, complete cds	P
AK313251.1	Homo sapiens cDNA, FLJ93757, Homo sapiens TDP-glucose 4,6-dehydratase (TGDS), mRNA	P
BC033675.1	Homo sapiens TDP-glucose 4,6-dehydratase, mRNA (cDNA clone MGC:45138 IMAGE:5175390), complete cds	PA
AF339778.1	Homo sapiens clone IMAGE:1567660, mRNA sequence	A
BC005284.1	Homo sapiens TDP-glucose 4,6-dehydratase, mRNA (cDNA clone IMAGE:3510977), partial cds	PA
AK303439.1	Homo sapiens cDNA FLJ50333 complete cds, moderately similar to dTDP-D-glucose 4,6-dehydratase (EC 4.2.1.46)	P

EST sequences (10 of 172) [Show all sequences]

AA976208.1	Clone IMAGE:1567660	lung	3' read
AI089175.1	Clone IMAGE:1634585	mixed	3' read	A
BX107099.1	Clone IMAGp998G0373_;_IMAGE:23160	brain		A
BX109198.1	Clone IMAGp998M053972_;_IMAGE:1567660	lung
AI168734.1	Clone IMAGE:1661281	mixed	3' read
AI189412.1	Clone IMAGE:1722888	placenta	3' read	A
AI206300.1	Clone IMAGE:1942038	uncharacterized tissue	3' read	A
AI199241.1	Clone IMAGE:1943882	prostate	3' read
AI224156.1	Clone IMAGE:1858511	mixed	3' read	A
AI347251.1	Clone IMAGE:2062934	intestine	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria