> Transmembrane protein 237 (TMEM237)
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UGID:132883     UniGene Hs.12319     Homo sapiens (human)   TMEM237
Transmembrane protein 237 (TMEM237)

Human protein-coding gene TMEM237. Represented by 215 ESTs from 105 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 132883 - Hs.12319]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001037850.1 TMEM237 gene product H. sapiens 100.0 407
XP_001156617.2 PREDICTED: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein isoform 1 P. troglodytes 99.8 407
NP_001032901.1 Tmem237 gene product M. musculus 89.8 394
XP_685343.4 PREDICTED: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein D. rerio 66.0 376
NP_001108263.1 transmembrane protein 237 X. laevis 65.8 386
Other hits (2 of 20) [Show all]SpeciesId(%)Len(aa)
NP_001244818.1 transmembrane protein 237 M. mulatta 98.5 407
XP_003907861.1 PREDICTED: transmembrane protein 237 isoform 2 P. anubis 98.5 407

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; connective tissue; kidney; eye; intestine; mixed; uncharacterized tissue; embryonic tissue; testis; pancreas; bone; bone marrow; larynx; uterus; ovary; muscle; prostate; placenta; adrenal gland; liver; trachea; mammary gland; skin; lung; ascites; mouth; thyroid; pituitary gland; ganglia; blood
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q33.2
UniSTS entry: Chr 2 RH47568
UniSTS entry: Chr 2 G65656
UniSTS entry: Chr 2 STS-N48800
UniSTS entry: Chr 2 RH15616
UniSTS entry: Chr 2 RH68361 [Map Viewer]
UniSTS entry: Chr 10 WI-20848 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

BX538000.1 Homo sapiens mRNA; cDNA DKFZp313L091 (from clone DKFZp313L091) PA
AK125841.1 Homo sapiens cDNA FLJ43853 fis, clone TESTI4006819, moderately similar to Alpha enolase (EC 4.2.1.11) PA
AK022836.1 Homo sapiens cDNA FLJ12774 fis, clone NT2RP2001663, moderately similar to ENOLASE (EC 4.2.1.11) A
NM_001044385.2 Homo sapiens transmembrane protein 237 (TMEM237), transcript variant 1, mRNA PA
BC013730.1 Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4, mRNA (cDNA clone IMAGE:3861305), partial cds PA
AB053301.1 Homo sapiens ALS2CR4 mRNA, complete cds P
AF212043.1 Homo sapiens potential LAG1 interactor mRNA, partial cds P
AK090601.1 Homo sapiens cDNA FLJ33282 fis, clone ASTRO2009118 P
AK304395.1 Homo sapiens cDNA FLJ58229 complete cds, highly similar to Amyotrophic lateral sclerosis 2 chromosomalregion candidate gene 4 protein P
AK303954.1 Homo sapiens cDNA FLJ58225 complete cds, highly similar to Amyotrophic lateral sclerosis 2 chromosomalregion candidate gene 4 protein P
NM_152388.3 Homo sapiens transmembrane protein 237 (TMEM237), transcript variant 2, mRNA PA
BC029611.1 Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4, mRNA (cDNA clone MGC:39837 IMAGE:5304046), complete cds PA

EST sequences (10 of 215) [Show all sequences]

AA908277.1 Clone IMAGE:1441643 mammary gland 3' read A
AA905365.1 Clone IMAGE:1506918 mixed 3' read A
AI147246.1 Clone IMAGE:1698386 uterus 3' read PA
AI087401.1 Clone IMAGE:1680899 skin 3' read A
BX095550.1 Clone IMAGp998B10618_;_IMAGE:279465 brain
AI206988.1 Clone IMAGE:1941406 uncharacterized tissue 3' read
CB143438.1 Clone L16HLK3-16-B09 liver 5' read P
CB117113.1 Clone L4SNU368-28-C06 liver 5' read
AI366812.1 Clone IMAGE:1935609 embryonic tissue 3' read A
AI382343.1 Clone IMAGE:2049551 embryonic tissue 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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