Crystallin, gamma A (CRYGA)

Restricted Expression:

soft tissue/muscle tissue tumor [show more like this]

EST Profile:

Approximate expression patterns inferred from EST sources.

GEO Profiles:

Experimental gene expression data (Gene Expression Omnibus).

cDNA Sources:

eye; embryonic tissue; connective tissue

NCBI

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Finding cDNAs

UGID:146292 UniGene Hs.122566 Homo sapiens (human) CRYGA

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Crystallin, gamma A (CRYGA)

Human protein-coding gene CRYGA. Represented by 14 ESTs from 5 cDNA libraries. EST representation biased toward soft tissue/muscle tissue tumor. Corresponds to reference sequence NM_014617.3. [UniGene 146292 - Hs.122566]

SELECTED PROTEIN SIMILARITIES

Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms		Species	Id(%)	Len(aa)
NP_001094072.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gamma-crystallin A	P. troglodytes	100.0	173
NP_055432.2 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	CRYGA gene product	H. sapiens	100.0	173
NP_031800.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gamma-crystallin A	M. musculus	84.5	173
NP_001116783.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	si:dkey-57a22.15 gene product	D. rerio	60.1	173
NP_001086145.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	crystallin, gamma C	X. laevis	60.0	174
Other hits (2 of 20) [Show all]		Species	Id(%)	Len(aa)
NP_001094290.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	gamma-crystallin A	M. mulatta	98.3	173
XP_003907932.1 Conserved domains (CDD) Gene summary Protein sequence Protein/EST matches (ProtEST) Protein/protein matches (BLink)	PREDICTED: gamma-crystallin A	P. anubis	98.3	173

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	2
Map position:	2q34
UniSTS entry:	Chr 2	GDB:181240

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

NM_014617.3	Homo sapiens crystallin, gamma A (CRYGA), mRNA	P
BC114456.1	Homo sapiens crystallin, gamma A, mRNA (cDNA clone MGC:138558 IMAGE:40014816), complete cds	P
EF426311.1	Homo sapiens gammaA-crystallin (CRYGA) mRNA, complete cds	P

EST sequences (14)

AI052518.1	Clone IMAGE:1676569	embryonic tissue	3' read	PA
BX281946.1	Clone IMAGp998G024256_;_IMAGE:1676569	embryonic tissue		P
BY794987.2	Clone HE0046.seq	eye	5' read	P
BG207174.1		connective tissue		PA
BM667439.1	Clone UI-E-DX0-agr-a-15-0-UI	eye	3' read	A
BM667614.1	Clone UI-E-DX0-ags-h-21-0-UI	eye	3' read	PA
BM698524.1	Clone UI-E-DX0-agr-a-15-0-UI	eye	5' read	P
BM698997.1	Clone UI-E-DX1-agw-l-14-0-UI	eye	5' read	PA
BM710792.1	Clone UI-E-DX0-ags-h-21-0-UI	eye	5' read	P
BM710815.1	Clone UI-E-DX0-ags-p-05-0-UI	eye	5' read
BU737436.1	Clone UI-E-DX1-agw-l-14-0-UI	eye	3' read	PA
AA404330.1	Clone IMAGE:772269	embryonic tissue	3' read	PA
AA404481.1	Clone IMAGE:772269	embryonic tissue	5' read	P
AA780079.1	Clone IMAGE:1033708	embryonic tissue	3' read	PA

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria