> WD repeat domain, phosphoinositide interacting 2 (WIPI2)
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UGID:146235     UniGene Hs.122363     Homo sapiens (human)   WIPI2 Order cDNA clone, Links
WD repeat domain, phosphoinositide interacting 2 (WIPI2)

Human protein-coding gene WIPI2. Represented by 757 ESTs from 300 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 146235 - Hs.122363]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003318335.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 2 isoform 3 P. troglodytes 100.0 453
NP_056425.1 WIPI2 gene product H. sapiens 100.0 453
XP_003895746.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 2 isoform 3 P. anubis 99.8 453
NP_848485.1 Wipi2 gene product M. musculus 98.4 444
NP_001080319.1 WD repeat domain phosphoinositide-interacting protein 2 X. laevis 95.4 434
NP_648184.1 Autophagy-specific gene 18, isoform A D. melanogaster 72.6 369
NP_956685.1 wipi1 gene product D. rerio 69.2 441
NP_741577.1 Protein ATG-18, isoform b C. elegans 50.3 348
Other hits (2 of 43) [Show all]SpeciesId(%)Len(aa)
XP_003210637.1 PREDICTED: WD repeat domain phosphoinositide-interacting protein 2-like M. gallopavo 99.0 399
NP_001007616.1 Wipi2 gene product R. norvegicus 98.9 444

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; mixed; lung; uncharacterized tissue; skin; placenta; intestine; pancreas; uterus; embryonic tissue; kidney; eye; liver; lymph; heart; prostate; stomach; bone; mammary gland; cervix; pharynx; trachea; thymus; bladder; tonsil; larynx; ascites; connective tissue; lymph node; ovary; adrenal gland; blood; muscle; bone marrow; mouth; thyroid; salivary gland; spleen; ear; ganglia; parathyroid; adipose tissue; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7p22.1
UniSTS entry: Chr 7 WI-17069 [Map Viewer]
UniSTS entry: Chr 7 RH12207 [Map Viewer]
UniSTS entry: Chr 7 A003P36 [Map Viewer]
UniSTS entry: Chr 7 RH93080
UniSTS entry: Chr 7 WI-20761 [Map Viewer]
UniSTS entry: Chr 7 RH45406 [Map Viewer]
UniSTS entry: Chr 1 D11S2921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (21)

AL080155.1 Homo sapiens mRNA; cDNA DKFZp434J154 (from clone DKFZp434J154) PA
BX537624.1 Homo sapiens mRNA; cDNA DKFZp686P02188 (from clone DKFZp686P02188) A
AK125007.1 Homo sapiens cDNA FLJ43017 fis, clone BRTHA2016577
AK124974.1 Homo sapiens cDNA FLJ42984 fis, clone BRTHA2008335 P
CR533530.1 Homo sapiens full open reading frame cDNA clone RZPDo834F0219D for gene DKFZP434J154, DKFZP434J154 protein; complete cds, incl. stopcodon P
NM_015610.3 Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 1, mRNA P
NM_016003.3 Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 2, mRNA P
AY691426.1 Homo sapiens WIPI-2 delta mRNA, complete cds, alternatively spliced P
AY691425.1 Homo sapiens WIPI-2 beta mRNA, complete cds, alternatively spliced P
AF151808.1 Homo sapiens CGI-50 protein mRNA, complete cds P
AK023041.1 Homo sapiens cDNA FLJ12979 fis, clone NT2RP2006334, highly similar to WD repeat domain phosphoinositide-interacting protein 2 P
AK024279.1 Homo sapiens cDNA FLJ14217 fis, clone NT2RP3003680, highly similar to WD repeat domain phosphoinositide-interacting protein 2 P
NM_001033520.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 5, mRNA P
NM_001033519.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 4, mRNA P
NM_001033518.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2 (WIPI2), transcript variant 3, mRNA P
BC004116.2 Homo sapiens WD repeat domain, phosphoinositide interacting 2, mRNA (cDNA clone MGC:11167 IMAGE:3842487), complete cds PA
BC007596.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2, mRNA (cDNA clone MGC:15650 IMAGE:3346710), complete cds PA
BC021200.2 Homo sapiens WD repeat domain, phosphoinositide interacting 2, mRNA (cDNA clone MGC:11392 IMAGE:3957981), complete cds PA
AK315468.1 Homo sapiens cDNA, FLJ96528 P
BC021068.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2, mRNA (cDNA clone IMAGE:2966543) PA
BC021012.1 Homo sapiens WD repeat domain, phosphoinositide interacting 2, mRNA (cDNA clone IMAGE:2966543) PA

EST sequences (10 of 757) [Show all sequences]

AA971423.1 Clone IMAGE:1584330 lung 3' read A
AA971851.1 Clone IMAGE:1584763 lung 3' read A
AA975243.1 Clone IMAGE:1588431 uncharacterized tissue 3' read A
AA987903.1 Clone IMAGE:1605116 lung 3' read
AI003235.1 Clone IMAGE:1685342 brain 3' read A
AA928004.1 Clone IMAGE:1541944 mixed 3' read A
AI004039.1 Clone IMAGE:1625953 mixed 3' read P
AI016079.1 Clone IMAGE:1638490 testis 3' read P
AI024297.1 Clone IMAGE:1642392 testis 3' read
AI026084.1 Clone IMAGE:1647303 parathyroid 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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