> Charged multivesicular body protein 2A (CHMP2A)
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UGID:132832     UniGene Hs.12107     Homo sapiens (human)   CHMP2A
Charged multivesicular body protein 2A (CHMP2A)

Human protein-coding gene CHMP2A. Represented by 351 ESTs from 195 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 132832 - Hs.12107]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_081161.1 Chmp2a gene product M. musculus 100.0 221
NP_001102376.1 Chmp2a gene product R. norvegicus 100.0 221
XP_001099219.1 PREDICTED: charged multivesicular body protein 2a-like isoform 4 M. mulatta 100.0 221
XP_003916326.1 PREDICTED: charged multivesicular body protein 2a isoform 1 P. anubis 100.0 221
XP_512956.2 PREDICTED: charged multivesicular body protein 2a isoform 3 P. troglodytes 100.0 221
NP_940818.1 CHMP2A gene product H. sapiens 100.0 221
XP_850536.1 PREDICTED: charged multivesicular body protein 2a isoform 2 C. lupus familiaris 100.0 221
NP_001029722.1 CHMP2A gene product B. taurus 99.5 221
XP_004015515.1 PREDICTED: charged multivesicular body protein 2a isoform 1 O. aries 99.5 221
XP_002721945.1 PREDICTED: chromatin modifying protein 2A O. cuniculus 99.5 221
NP_001085225.1 charged multivesicular body protein 2a X. laevis 94.1 219
NP_998682.1 bc2 gene product D. rerio 93.6 219
NP_651455.1 vps2 D. melanogaster 79.3 255
NP_496717.1 Protein VPS-2 C. elegans 76.0 236
NP_565336.1 vacuolar protein sorting-associated protein 2-1 A. thaliana 62.5 224
XP_001698676.1 subunit of the ESCRT-III complex C. reinhardtii 59.0 222
XP_956699.1 hypothetical protein NCU00435 N. crassa 55.6 224
NP_012924.2 Did4p S. cerevisiae 50.7 229
Other hits (2 of 47) [Show all]SpeciesId(%)Len(aa)
XP_003361783.1 PREDICTED: charged multivesicular body protein 2a-like, partial S. scrofa 99.4 171
XP_001495679.1 PREDICTED: charged multivesicular body protein 2a-like E. caballus 96.1 205

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; lung; placenta; embryonic tissue; ovary; adrenal gland; skin; mixed; kidney; uncharacterized tissue; uterus; mammary gland; esophagus; bone marrow; umbilical cord; liver; stomach; lymph node; pancreas; eye; intestine; prostate; lymph; muscle; heart; blood; thyroid; thymus; epididymis; larynx; cervix; testis; vascular; ascites; bone; pituitary gland; connective tissue; spleen; ear; mouth; tonsil; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 19
Map position: 19q
UniSTS entry: Chr 19 SHGC-30173 [Map Viewer]
UniSTS entry: Chr 1 D11S3114
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (8)

BT007298.1 Homo sapiens putative breast adenocarcinoma marker (32kD) mRNA, complete cds P
NM_198426.1 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 2, mRNA PA
CR457002.1 Homo sapiens full open reading frame cDNA clone RZPDo834F085D for gene BC-2, putative breast adenocarcinoma marker (32kD); complete cds, incl. stopcodon P
NM_014453.2 Homo sapiens charged multivesicular body protein 2A (CHMP2A), transcript variant 1, mRNA PA
AY364248.1 Homo sapiens clone peg2078 putative breast adenocarcinoma marker (BC2) mRNA, complete cds P
BC002502.2 Homo sapiens chromatin modifying protein 2A, mRNA (cDNA clone MGC:806 IMAGE:3051024), complete cds PA
AK311974.1 Homo sapiens cDNA, FLJ92247, Homo sapiens putative breast adenocarcinoma marker (32kD) (BC-2),mRNA P
AF042384.1 Homo sapiens BC-2 protein mRNA, complete cds PA

EST sequences (10 of 351) [Show all sequences]

AA836807.1 Clone IMAGE:1422644 kidney P
AA922324.1 Clone IMAGE:1486248 mouth 3' read
AA994333.1 Clone IMAGE:1628129 mixed 3' read PA
AI000435.1 Clone IMAGE:1637698 mammary gland 3' read PA
AA902703.1 Clone IMAGE:1519416 uncharacterized tissue 3' read PA
AI004274.1 Clone IMAGE:1625989 mixed 3' read P
AI017246.1 Clone IMAGE:1636269 kidney 3' read PA
AI051265.1 Clone IMAGE:1669200 brain 3' read PA
AI096513.1 Clone IMAGE:1704552 brain 3' read PA
CB049357.1 Clone IMAGE:3271295 prostate 5' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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