> Cyclin-dependent kinase 6 (CDK6)
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UGID:145508     UniGene Hs.119882     Homo sapiens (human)   CDK6 Order cDNA clone, Links
Cyclin-dependent kinase 6 (CDK6)

Human protein-coding gene CDK6. Represented by 567 ESTs from 203 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 145508 - Hs.119882]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001100307.1 PREDICTED: cell division protein kinase 6 M. mulatta 100.0 325
XP_001167181.1 PREDICTED: cyclin-dependent kinase 6 isoform 1 P. troglodytes 100.0 325
NP_001138778.1 CDK6 gene product H. sapiens 100.0 325
XP_003896377.1 PREDICTED: cyclin-dependent kinase 6 isoform 1 P. anubis 100.0 215
XP_004008248.1 PREDICTED: cyclin-dependent kinase 6 O. aries 99.7 282
NP_034003.1 Cdk6 gene product M. musculus 98.2 325
NP_001137525.1 cyclin-dependent kinase 6 D. rerio 92.6 269
NP_001088955.1 cyclin-dependent kinase 6 X. laevis 75.1 297
NP_566911.1 cyclin-dependent kinase A-1 A. thaliana 52.4 288
NP_477196.1 Cyclin-dependent kinase 4, isoform B D. melanogaster 52.4 288
XP_001698637.1 cyclin dependent protein kinase C. reinhardtii 50.7 288
NP_499783.1 Protein CDK-5 C. elegans 50.5 285
NP_009718.3 Cdc28p S. cerevisiae 50.3 290
XP_960117.1 cell division control protein 2 N. crassa 48.2 311
Other hits (2 of 64) [Show all]SpeciesId(%)Len(aa)
XP_001493553.2 PREDICTED: cyclin-dependent kinase 6 E. caballus 99.4 325
XP_002713851.1 PREDICTED: cyclin-dependent kinase 6 O. cuniculus 99.4 325

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: uncharacterized tissue; mixed; brain; embryonic tissue; stomach; lung; liver; esophagus; skin; testis; lymph node; kidney; amniotic fluid; eye; intestine; thymus; adrenal gland; larynx; pineal gland; prostate; trachea; spinal cord; lymph; ascites; connective tissue; blood; placenta; pancreas; bone marrow; mammary gland; mouth; heart; muscle; parathyroid; bladder; uterus; salivary gland; bone; ovary; vascular; tonsil
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q21-q22
UniSTS entry: Chr 7 SHGC-33519 [Map Viewer]
UniSTS entry: Chr 7 RH17944
UniSTS entry: Chr 7 RH79066 [Map Viewer]
UniSTS entry: Chr 7 RH66680 [Map Viewer]
UniSTS entry: Chr 7 SHGC-35227 [Map Viewer]
UniSTS entry: Chr 7 RH15849
UniSTS entry: Chr 7 CDK6
UniSTS entry: Chr 7 G49183
UniSTS entry: Chr 7 G36998
UniSTS entry: Chr 7 STS-X66365
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (13)

BC052264.1 Homo sapiens cyclin-dependent kinase 6, mRNA (cDNA clone MGC:59692 IMAGE:6377987), complete cds PA
NM_001259.6 Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant 1, mRNA PA
BC063591.1 Homo sapiens cDNA clone IMAGE:4520413, partial cds A
BC065026.1 Homo sapiens cDNA clone IMAGE:6043861, partial cds A
AK000660.1 Homo sapiens cDNA FLJ20653 fis, clone KAT01739 A
AK172791.1 Homo sapiens cDNA FLJ23952 fis, clone HEP10212 A
AB073601.1 Homo sapiens primary hepatoblastoma cDNA, clone:HKMT0647, full insert sequence A
BC012914.1 Homo sapiens cyclin-dependent kinase 6, mRNA (cDNA clone IMAGE:4538214), partial cds A
AK055922.1 Homo sapiens cDNA FLJ31360 fis, clone MESAN2000572
AK313491.1 Homo sapiens cDNA, FLJ94044, Homo sapiens cyclin-dependent kinase 6 (CDK6), mRNA P
BC027989.1 Homo sapiens cyclin-dependent kinase 6, mRNA (cDNA clone IMAGE:4995539) A
NM_001145306.1 Homo sapiens cyclin-dependent kinase 6 (CDK6), transcript variant 2, mRNA PA
X66365.1 H.sapiens mRNA PLSTIRE for serine/threonine protein kinase P

EST sequences (10 of 567) [Show all sequences]

AI015629.1 Clone IMAGE:1638771 testis 3' read P
AI022731.1 Clone IMAGE:1654176 mixed 3' read
AI023175.1 Clone IMAGE:1651799 skin 3' read
AA922068.1 Clone IMAGE:1543989 mixed 3' read
AI032086.1 Clone IMAGE:1654271 mixed 3' read
AI034267.1 Clone IMAGE:1646946 parathyroid 3' read P
AI038906.1 Clone IMAGE:1664198 skin 3' read
T26677.1 Clone LLAB8B8 brain 5' read
AI042637.1 Clone IMAGE:1668147 parathyroid 3' read P
AI085767.1 Clone IMAGE:1661145 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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