> Ubiquitin protein ligase E3C (UBE3C)
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UGID:145261     UniGene Hs.118351     Homo sapiens (human)   UBE3C
Ubiquitin protein ligase E3C (UBE3C)

Human protein-coding gene UBE3C. Represented by 504 ESTs from 254 cDNA libraries. Corresponds to reference sequence NM_014671.2. [UniGene 145261 - Hs.118351]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003896975.1 PREDICTED: ubiquitin-protein ligase E3C P. anubis 100.0 1082
XP_528010.3 PREDICTED: ubiquitin-protein ligase E3C P. troglodytes 100.0 1082
NP_055486.2 UBE3C gene product H. sapiens 100.0 1082
XP_002803585.1 PREDICTED: ubiquitin-protein ligase E3C-like M. mulatta 99.7 971
NP_598668.1 ubiquitin-protein ligase E3C M. musculus 96.4 1082
NP_001080799.1 ubiquitin protein ligase E3C X. laevis 91.8 1079
NP_956767.1 ube3c gene product D. rerio 84.8 993
NP_611896.1 CG3356 D. melanogaster 62.4 456
NP_001118648.1 E3 ubiquitin-protein ligase UPL6 A. thaliana 49.5 399
NP_011374.1 ubiquitin-ubiquitin ligase HUL5 S. cerevisiae 49.1 176
XP_001695431.1 predicted protein C. reinhardtii 48.6 293
XP_960426.2 hypothetical protein NCU04800 N. crassa 48.1 182
NP_495842.1 Protein D2085.4 C. elegans 46.2 251
Other hits (2 of 55) [Show all]SpeciesId(%)Len(aa)
XP_002715065.1 PREDICTED: ubiquitin protein ligase E3C O. cuniculus 99.0 1082
XP_001915096.1 PREDICTED: LOW QUALITY PROTEIN: ubiquitin-protein ligase E3C-like E. caballus 98.0 1062

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; prostate; muscle; cervix; embryonic tissue; pharynx; intestine; uncharacterized tissue; mixed; thyroid; skin; uterus; lymph node; heart; kidney; lung; placenta; mammary gland; liver; vascular; connective tissue; eye; umbilical cord; mouth; pancreas; adrenal gland; blood; ovary; bone marrow; stomach; bladder; esophagus; thymus; trachea; epididymis; larynx; ear; lymph; ascites; nerve; bone; parathyroid; spinal cord; adipose tissue; pituitary gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 7
Map position: 7q36.3
UniSTS entry: Chr 7 RH25250 [Map Viewer]
UniSTS entry: Chr 7 D7S2872
UniSTS entry: Chr 7 D7S2380
UniSTS entry: Chr 7 STS-D13635 [Map Viewer]
UniSTS entry: Chr 7 SHGC-58446
UniSTS entry: Chr 1 D15S1477
UniSTS entry: Chr 7 RH69625 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (7)

AK127280.1 Homo sapiens cDNA FLJ45347 fis, clone BRHIP3011082, highly similar to Homo sapiens ubiquitin-protein isopeptide ligase (E3) P
NM_014671.2 Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA PA
BC014029.2 Homo sapiens ubiquitin protein ligase E3C, mRNA (cDNA clone MGC:19944 IMAGE:4541634), complete cds PA
D13635.1 Homo sapiens KIAA0010 mRNA, partial cds P
BC026241.1 Homo sapiens ubiquitin protein ligase E3C, mRNA (cDNA clone IMAGE:4696496), complete cds PA
AK098447.1 Homo sapiens cDNA FLJ25581 fis, clone JTH09270
AK295138.1 Homo sapiens cDNA FLJ61262 complete cds, highly similar to Ubiquitin-protein ligase E3C (EC 6.3.2.-) P

EST sequences (10 of 504) [Show all sequences]

R18659.1 Clone IMAGE:30526 brain 5' read
AI082843.1 Clone IMAGE:1662441 mixed 3' read
BX095171.1 Clone IMAGp998D23728_;_IMAGE:321766 parathyroid
AI207292.1 Clone IMAGE:1759071 placenta 3' read A
CB148987.1 Clone L17N670205-1-E08 liver 5' read
CB108671.1 Clone L3SNU475-27-G09 liver 5' read A
CB135281.1 Clone L5HLK1-32-C08 liver 5' read P
CB124141.1 Clone L5HLK1s1-11-A09 liver 5' read P
CB124362.1 Clone L5HLK1s1-9-E06 liver 5' read
CB126638.1 Clone L5HLK1s1-22-B02 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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