> FYVE, RhoGEF and PH domain containing 4 (FGD4)
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UGID:145160     UniGene Hs.117835     Homo sapiens (human)   FGD4 Order cDNA clone, Links
FYVE, RhoGEF and PH domain containing 4 (FGD4)

Human protein-coding gene FGD4. Represented by 205 ESTs from 111 cDNA libraries. Corresponds to reference sequence NM_139241.2. [UniGene 145160 - Hs.117835]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_640334.2 FGD4 gene product H. sapiens 100.0 765
XP_520721.3 PREDICTED: FYVE, RhoGEF and PH domain-containing protein 4 isoform 7 P. troglodytes 99.9 877
NP_631978.1 Fgd4 gene product M. musculus 92.0 765
NP_001171404.1 fgd4a gene product D. rerio 74.0 701
Other hits (2 of 22) [Show all]SpeciesId(%)Len(aa)
XP_001084857.2 PREDICTED: FYVE, RhoGEF and PH domain-containing protein 4 isoform 2 M. mulatta 99.2 850
XP_003906235.1 PREDICTED: FYVE, RhoGEF and PH domain-containing protein 4 P. anubis 98.8 857

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: testis; brain; blood; prostate; kidney; pancreas; uncharacterized tissue; mixed; uterus; embryonic tissue; ovary; thyroid; muscle; salivary gland; spleen; ascites; eye; intestine; stomach; liver; bladder; mammary gland; placenta; skin; vascular; esophagus; trachea; connective tissue; thymus; heart; adipose tissue; pineal gland; parathyroid; lung; bone; umbilical cord
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 12
Map position: 12p11.21
UniSTS entry: Chr 12 RH44796
UniSTS entry: Chr 12 FGD4__4996
UniSTS entry: Chr 1 D15S1477
UniSTS entry: Chr 1 G44334
UniSTS entry: Chr 1 G60245
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

BC045552.1 Homo sapiens FYVE, RhoGEF and PH domain containing 4, mRNA (cDNA clone MGC:57222 IMAGE:4831180), complete cds PA
AK124654.1 Homo sapiens cDNA FLJ42663 fis, clone BRAMY2019963
BC063403.1 Homo sapiens cDNA clone IMAGE:5192839, partial cds PA
BC096746.1 Homo sapiens FYVE, RhoGEF and PH domain containing 4, mRNA (cDNA clone IMAGE:5298083), with apparent retained intron PA
AK057294.1 Homo sapiens cDNA FLJ32732 fis, clone TESTI2001141, highly similar to Rattus norvegicus actin-filament binding protein Frabin mRNA P
NM_139241.2 Homo sapiens FYVE, RhoGEF and PH domain containing 4 (FGD4), mRNA PA
AK091689.1 Homo sapiens cDNA FLJ34370 fis, clone FEBRA2017154 A
AL832064.1 Homo sapiens mRNA; cDNA DKFZp313E1818 (from clone DKFZp313E1818) PA
AK303334.1 Homo sapiens cDNA FLJ56188 complete cds, highly similar to FYVE, RhoGEF and PH domain-containing protein4 P
AK297025.1 Homo sapiens cDNA FLJ55905 complete cds, highly similar to FYVE, RhoGEF and PH domain-containing protein 4 P
BC039708.1 Homo sapiens FYVE, RhoGEF and PH domain containing 4, mRNA (cDNA clone IMAGE:5194873), with apparent retained intron PA

EST sequences (10 of 205) [Show all sequences]

AA921849.1 Clone IMAGE:1543892 mixed 3' read PA
AI033884.1 Clone IMAGE:1646454 parathyroid 3' read
BX104161.1 Clone IMAGp998H124885_;_IMAGE:1987643 uterus A
BX114476.1 Clone IMAGp998N246086_;_IMAGE:2447831 stomach A
AI222351.1 Clone IMAGE:1843682 mixed 3' read A
AI251842.1 Clone IMAGE:1978107 brain 3' read A
AI263488.1 Clone IMAGE:1855812 mixed 3' read
CB162006.1 Clone L17N670205n1-16-A10 liver 5' read
AI276233.1 Clone IMAGE:1878260 mixed 3' read
CB124491.1 Clone L14ChoiCK0-1-B02 liver 5' read P


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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