> Secreted protein, acidic, cysteine-rich (osteonectin) (SPARC)
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UGID:144119     UniGene Hs.111779     Homo sapiens (human)   SPARC Order cDNA clone, Links
Secreted protein, acidic, cysteine-rich (osteonectin) (SPARC)

Human protein-coding gene SPARC. Represented by 4262 ESTs from 582 cDNA libraries. Corresponds to reference sequence NM_003118.3. [UniGene 144119 - Hs.111779]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_003900448.1 PREDICTED: SPARC P. anubis 100.0 302
XP_001168719.1 PREDICTED: SPARC isoform 6 P. troglodytes 100.0 302
NP_003109.1 SPARC gene product H. sapiens 100.0 302
NP_776889.1 SPARC gene product B. taurus 99.7 303
NP_001159674.1 SPARC gene product O. aries 99.7 302
NP_033268.1 Sparc gene product M. musculus 99.7 301
NP_001079590.1 secreted protein, acidic, cysteine-rich (osteonectin) precursor X. laevis 90.7 299
NP_001001942.1 sparc gene product D. rerio 88.0 290
Other hits (2 of 19) [Show all]SpeciesId(%)Len(aa)
XP_001101364.2 PREDICTED: SPARC M. mulatta 99.4 325
XP_003639058.1 PREDICTED: SPARC-like C. lupus familiaris 99.3 302

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; placenta; embryonic tissue; skin; bone; testis; connective tissue; uterus; pancreas; eye; ear; uncharacterized tissue; lung; bone marrow; kidney; intestine; stomach; mixed; heart; liver; mammary gland; umbilical cord; adrenal gland; thyroid; prostate; ganglia; ovary; muscle; mouth; vascular; nerve; parathyroid; epididymis; larynx; bladder; pharynx; thymus; amniotic fluid; spleen; salivary gland; trachea; adipose tissue; lymph node; cervix; esophagus; pituitary gland; lymph; blood; spinal cord; pineal gland
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 5
Map position: 5q31.3-q32
UniSTS entry: Chr 5 RH68620
UniSTS entry: Chr 5 STS-J03040 [Map Viewer]
UniSTS entry: Chr 5 RH71413
UniSTS entry: RH47515
UniSTS entry: Chr 5 D5S444E [Map Viewer]
UniSTS entry: Chr 5 GDB:294200
UniSTS entry: Chr 5 A007I34
UniSTS entry: RH41219
UniSTS entry: Chr 1 D1S3690
UniSTS entry: Chr 5 SPARC_1369
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

AK126525.1 Homo sapiens cDNA FLJ44561 fis, clone UTERU3008671, weakly similar to SPARC precursor P
NM_003118.3 Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin) (SPARC), mRNA PA
AY545555.1 Homo sapiens cysteine-rich protein (SPARC) mRNA, partial cds
BC072457.1 Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin), mRNA (cDNA clone MGC:88065 IMAGE:6186685), complete cds PA
CR456799.1 Homo sapiens full open reading frame cDNA clone RZPDo834D0918D for gene SPARC, secreted protein, acidic, cysteine-rich (osteonectin); complete cds, incl. stopcodon P
J03040.1 Human SPARC/osteonectin mRNA, complete cds PA
BC004974.1 Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin), mRNA (cDNA clone MGC:3651 IMAGE:2906092), complete cds PA
BC008011.1 Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin), mRNA (cDNA clone MGC:15881 IMAGE:3529445), complete cds PA
AK315591.1 Homo sapiens cDNA, FLJ96669, highly similar to Homo sapiens secreted protein, acidic, cysteine-rich (osteonectin)(SPARC), mRNA P
Y00755.1 Human mRNA for extracellular matrix protein BM-40 P
AK096969.1 Homo sapiens cDNA FLJ39650 fis, clone SMINT2005075, highly similar to SPARC PRECURSOR P
AK299441.1 Homo sapiens cDNA FLJ55667 complete cds, highly similar to Secreted protein acidic and rich in cysteine P

EST sequences (10 of 4262) [Show all sequences]

AA954174.1 Clone IMAGE:1591333 kidney 3' read A
AA955019.1 Clone IMAGE:1591269 kidney 3' read A
AA961027.1 Clone IMAGE:1575130 kidney 3' read A
AA865415.1 Clone IMAGE:1459218 kidney 3' read A
AA961397.1 Clone IMAGE:1597839 uncharacterized tissue 3' read A
AA961428.1 Clone IMAGE:1599547 uncharacterized tissue 3' read A
AA962059.1 Clone IMAGE:1592606 kidney 3' read A
AA903520.1 Clone IMAGE:1517440 uncharacterized tissue 3' read A
AA968525.1 Clone IMAGE:1592144 kidney 3' read A
AA969765.1 Clone IMAGE:1573410 kidney 3' read A


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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