> ATP-binding cassette, sub-family B (MDR/TAP), member 6 (ABCB6)
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UGID:143806     UniGene Hs.107911     Homo sapiens (human)   ABCB6 Order cDNA clone, Links
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (ABCB6)

Human protein-coding gene ABCB6. Represented by 376 ESTs from 152 cDNA libraries. Corresponds to reference sequence NM_005689.2. [UniGene 143806 - Hs.107911]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_005680.1 ABCB6 gene product H. sapiens 100.0 841
XP_001161097.1 PREDICTED: ATP-binding cassette sub-family B member 6, mitochondrial isoform 5 P. troglodytes 99.8 842
NP_076221.1 Abcb6 gene product M. musculus 92.7 839
NP_001139165.1 ATP-binding cassette sub-family B member 6, mitochondrial D. rerio 75.5 799
NP_650503.1 heavy metal tolerance factor 1 D. melanogaster 63.3 810
NP_001022812.1 Protein HMT-1 C. elegans 62.9 595
NP_200635.1 ABC transporter B family member 25 A. thaliana 55.2 591
XP_001690340.1 half-size ABC transporter, membrane protein C. reinhardtii 54.3 579
NP_001081394.1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 X. laevis 53.4 277
XP_956997.2 hypothetical protein NCU00010 N. crassa 51.4 510
NP_014030.1 ATP-binding cassette Fe/S cluster precursor transporter ATM1 S. cerevisiae 51.3 318
Other hits (2 of 66) [Show all]SpeciesId(%)Len(aa)
XP_003908026.1 PREDICTED: ATP-binding cassette sub-family B member 6, mitochondrial P. anubis 99.4 842
XP_002799099.1 PREDICTED: ATP-binding cassette sub-family B member 6, mitochondrial-like isoform 1 M. mulatta 98.9 842

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; ovary; testis; uncharacterized tissue; lung; mammary gland; mixed; embryonic tissue; skin; prostate; pancreas; muscle; eye; blood; kidney; liver; bone marrow; intestine; placenta; lymph; mouth; thyroid; heart; thymus; adrenal gland; cervix; stomach; ascites; connective tissue; uterus; larynx; nerve; salivary gland; bone; lymph node; pharynx
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 2
Map position: 2q36
UniSTS entry: Chr 2 WI-20003 [Map Viewer]
UniSTS entry: Chr 2 RH103428
UniSTS entry: Chr 2 D2S2921
UniSTS entry: Chr 2 RH121051
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF070598.1 Homo sapiens clone 24410 ABC transporter mRNA, partial cds PA
AK172812.1 Homo sapiens cDNA FLJ23973 fis, clone HEP18305, highly similar to ATP-binding cassette, sub-family B, member 6, mitochondrial precursor PA
NM_005689.2 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 6 (ABCB6), nuclear gene encoding mitochondrial protein, mRNA PA
AJ289233.2 Homo sapiens mRNA for ABC transporter umat (ABCB6 gene) P
AF076775.1 Homo sapiens MT-ABC transporter (MTABC) mRNA, complete cds P
AK026067.1 Homo sapiens cDNA: FLJ22414 fis, clone HRC08477, highly similar to AF070598 Homo sapiens clone 24410 ABC transporter mRNA PA
AF308472.1 Homo sapiens ATP-binding cassette half-transporter (PRP) mRNA, complete cds PA
BC000559.2 Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 6, mRNA (cDNA clone MGC:3021 IMAGE:3162881), complete cds PA
AK057026.1 Homo sapiens cDNA FLJ32464 fis, clone SKNMC1000251, highly similar to Homo sapiens MT-ABC transporter (MTABC) mRNA P
U66673.1 Homo sapiens clone EST45597 mRNA sequence P
HQ013240.1 Homo sapiens clone pSWC1FB-1 minisatellite-associated sequence

EST sequences (10 of 376) [Show all sequences]

AA972284.1 Clone IMAGE:1584062 mixed 3' read A
AI053412.1 Clone IMAGE:1862573 ovary 3' read A
AI053823.1 Clone IMAGE:1862240 ovary 3' read A
AI053844.1 Clone IMAGE:1862245 ovary 3' read A
AI054318.1 Clone IMAGE:1862533 ovary 3' read A
AA947610.1 Clone IMAGE:1590214 kidney 3' read
AI149691.1 Clone IMAGE:1752724 testis 3' read A
AI150164.1 Clone IMAGE:1751881 testis 3' read PA
AI193721.1 Clone IMAGE:1744551 lung 3' read A
AI207097.1 Clone IMAGE:1754299 testis 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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