> Soc-2 suppressor of clear homolog (C. elegans) (SHOC2)
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UGID:143287     UniGene Hs.104315     Homo sapiens (human)   SHOC2
Soc-2 suppressor of clear homolog (C. elegans) (SHOC2)

Human protein-coding gene SHOC2. Represented by 371 ESTs from 158 cDNA libraries. Corresponds to 2 reference sequences (different isoforms). [UniGene 143287 - Hs.104315]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
XP_001087610.1 PREDICTED: leucine-rich repeat protein SHOC-2 isoform 3 M. mulatta 100.0 581
XP_521602.2 PREDICTED: leucine-rich repeat protein SHOC-2 isoform 2 P. troglodytes 100.0 581
NP_031399.2 SHOC2 gene product H. sapiens 100.0 581
XP_535013.2 PREDICTED: leucine-rich repeat protein SHOC-2 isoform 1 C. lupus familiaris 100.0 581
XP_001496623.1 PREDICTED: leucine-rich repeat protein SHOC-2 E. caballus 100.0 581
XP_001927528.1 PREDICTED: leucine-rich repeat protein SHOC-2 S. scrofa 100.0 581
NP_001095413.1 SHOC2 gene product B. taurus 100.0 581
XP_004020244.1 PREDICTED: leucine-rich repeat protein SHOC-2 isoform 1 O. aries 100.0 581
XP_003904303.1 PREDICTED: leucine-rich repeat protein SHOC-2 P. anubis 99.8 581
NP_001161977.1 Shoc2 gene product M. musculus 99.1 581
NP_001080350.1 leucine-rich repeat protein SHOC-2 X. laevis 95.7 576
NP_001038251.1 shoc2 gene product D. rerio 93.9 560
NP_732231.2 Sur-8, isoform A D. melanogaster 65.7 521
NP_001021259.1 Protein SOC-2, isoform a C. elegans 60.7 552
Other hits (2 of 28) [Show all]SpeciesId(%)Len(aa)
NP_001013173.1 Shoc2 gene product R. norvegicus 99.1 581
XP_001513272.2 PREDICTED: leucine-rich repeat protein SHOC-2 O. anatinus 98.9 536

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; uterus; lymph node; muscle; uncharacterized tissue; intestine; connective tissue; embryonic tissue; lung; heart; ovary; blood; esophagus; vascular; mouth; trachea; mixed; placenta; bone; liver; mammary gland; bone marrow; stomach; prostate; skin; bladder; eye; cervix; kidney; pancreas; thyroid; thymus; adrenal gland; pharynx; larynx; nerve; pineal gland; adipose tissue; parathyroid; ganglia
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 10
Map position: 10q25
UniSTS entry: Chr 10 G20338
UniSTS entry: Chr 10 A005M36 [Map Viewer]
UniSTS entry: Chr 10 RH103645
UniSTS entry: Chr 10 SHOC2_8774
UniSTS entry: RH80921
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (11)

AF054828.1 Homo sapiens leucine-rich repeat protein SHOC-2 (SHOC-2) mRNA, complete cds P
AF068920.1 Homo sapiens Ras-binding protein SUR-8 mRNA, complete cds P
BC044752.1 Homo sapiens soc-2 suppressor of clear homolog (C. elegans), mRNA (cDNA clone IMAGE:4826955) PA
AB020669.1 Homo sapiens mRNA for KIAA0862 protein, partial cds P
BC050445.1 Homo sapiens soc-2 suppressor of clear homolog (C. elegans), mRNA (cDNA clone MGC:54207 IMAGE:6067669), complete cds PA
BX649055.1 Homo sapiens mRNA; cDNA DKFZp779A2425 (from clone DKFZp779A2425) PA
NM_007373.3 Homo sapiens soc-2 suppressor of clear homolog (C. elegans) (SHOC2), transcript variant 1, mRNA PA
AK292833.1 Homo sapiens cDNA FLJ76498 complete cds, highly similar to Homo sapiens soc-2 suppressor of clear homolog (C. elegans) (SHOC2), mRNA P
AK090820.1 Homo sapiens cDNA FLJ33501 fis, clone BRAMY2004363, highly similar to Leucine-rich repeat protein SHOC-2 P
AK293271.1 Homo sapiens cDNA FLJ60412 complete cds, highly similar to Leucine-rich repeat protein SHOC-2 P
NM_001269039.1 Homo sapiens soc-2 suppressor of clear homolog (C. elegans) (SHOC2), transcript variant 2, mRNA PA

EST sequences (10 of 371) [Show all sequences]

AA961164.1 Clone IMAGE:1578910 mixed 3' read A
CB047563.1 Clone IMAGE:3253404 kidney 5' read A
BX091749.1 Clone IMAGp998H21204_;_IMAGE:139844 placenta
R25429.1 Clone IMAGE:132267 placenta 5' read
R26259.1 Clone IMAGE:132267 placenta 3' read
AI206628.1 Clone IMAGE:1942896 uncharacterized tissue 3' read
AI208301.1 Clone IMAGE:1837132 testis 3' read
AI202318.1 Clone IMAGE:1943461 prostate 3' read A
AI262963.1 Clone IMAGE:2028280 kidney 3' read
AI268184.1 Clone IMAGE:1880499 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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