C-ros oncogene 1 , receptor tyrosine kinase (ROS1)

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UGID:130904 UniGene Hs.1041 Homo sapiens (human) ROS1

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C-ros oncogene 1 , receptor tyrosine kinase (ROS1)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_002935.2	proto-oncogene c-ros-1 protein precursor	H. sapiens	100.0	2346
NP_035412.2	Ros1 proto-oncogene precursor	M. musculus	81.0	2339

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources.
	GEO profiles:	Experimental gene expression data (Gene Expression Omnibus).
	cDNA Sources:	lung; mixed; liver; vascular; brain; connective tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:	6
Map position:	6q22
UniSTS entry:	Chr 6	RH69070
UniSTS entry:	Chr 6	D6S1873

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (5)

M13880.1	Human mcf3 (rearranged ros1) proto-oncogene mRNA encoding a transmembrane protein kinase, 3' end	P
NM_002944.2	Homo sapiens c-ros oncogene 1 , receptor tyrosine kinase (ROS1), mRNA	P
M34353.1	Human transmembrane tyrosine-specific protein kinase (ROS1) mRNA, complete cds	P
EU236947.1	Homo sapiens SLC34A2/ROS fusion protein short isoform (SLC34A2/ROS1 fusion) mRNA, complete cds	P
BC144556.1	Homo sapiens cDNA clone IMAGE:9053084	PA

EST sequences (11)

BX093867.1	Clone IMAGp998E22689_;_IMAGE:306813	lung
CB118390.1	Clone L8SCK0-18-F09	liver	5' read
AI280391.1	Clone IMAGE:1880054	mixed	3' read
BP204713.1	Clone CAS03151	vascular	5' read	P
BP293481.1	Clone LNG12211	lung	5' read	P
DA335857.1	Clone BRHIP3036042	brain	5' read	P
BG460242.1		connective tissue		P
N79051.1	Clone IMAGE:306813	lung	3' read
W24195.1	Clone IMAGE:306789	lung	5' read	P
W24201.1	Clone IMAGE:306813	lung	5' read	P
AA913573.1	Clone IMAGE:1525202	mixed	3' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria