> C-ros oncogene 1 , receptor tyrosine kinase (ROS1)
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UGID:130904     UniGene Hs.1041     Homo sapiens (human)   ROS1 Links
C-ros oncogene 1 , receptor tyrosine kinase (ROS1)

Human protein-coding gene ROS1. Represented by 11 ESTs from 8 cDNA libraries. Corresponds to reference sequence NM_002944.2. [UniGene 130904 - Hs.1041]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_002935.2 ROS1 gene product H. sapiens 100.0 2346
NP_001087392.1 ezrin X. laevis 87.6 364
NP_001025456.1 ezrb gene product D. rerio 85.4 364
NP_035412.2 Ros1 gene product M. musculus 81.0 2339
NP_525082.2 moesin, isoform D D. melanogaster 72.2 356
NP_491559.1 Protein ERM-1, isoform a C. elegans 72.0 353
Other hits (2 of 40) [Show all]SpeciesId(%)Len(aa)
XP_527487.2 PREDICTED: proto-oncogene tyrosine-protein kinase ROS P. troglodytes 99.2 2346
XP_001110859.2 PREDICTED: proto-oncogene tyrosine-protein kinase ROS M. mulatta 96.9 2345

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: lung; mixed; liver; vascular; brain; connective tissue
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 6
Map position: 6q22
UniSTS entry: Chr 6 RH69070
UniSTS entry: Chr 6 D6S1873 [Map Viewer]
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (12)

M13880.1 Human mcf3 (rearranged ros1) proto-oncogene mRNA encoding a transmembrane protein kinase, 3' end P
NM_002944.2 Homo sapiens c-ros oncogene 1 , receptor tyrosine kinase (ROS1), mRNA P
M34353.1 Human transmembrane tyrosine-specific protein kinase (ROS1) mRNA, complete cds P
BC144556.1 Homo sapiens cDNA clone IMAGE:9053084 PA
AB698667.1 Homo sapiens EZR-ROS1 mRNA for EZR-ROS1 fusion protein, complete cds P
AB795246.1 Homo sapiens EZR-ROS1_E10;R34 mRNA for EZR-ROS1_E10;R34 fusion protein, complete cds
AB795244.1 Homo sapiens CD74-ROS1_C6;R32 mRNA for CD74-ROS1_C6;R32 fusion protein, complete cds
AB795242.1 Homo sapiens SDC4-ROS1_S4;R34 mRNA for SDC4-ROS1_S4;R34 fusion protein, complete cds
AB795240.1 Homo sapiens SDC4-ROS1_S2;R32 mRNA for SDC4-ROS1_S2;R32 fusion protein, complete cds
AB795245.1 Homo sapiens CD74-ROS1_C6;R34 mRNA for CD74-ROS1_C6;R34 fusion protein, complete cds
AB795241.1 Homo sapiens SDC4-ROS1_S4;R32 mRNA for SDC4-ROS1_S4;R32 fusion protein, complete cds
AB795239.1 Homo sapiens TPM3-ROS1 mRNA for TPM3-ROS1 fusion protein, complete cds

EST sequences (11)

BX093867.1 Clone IMAGp998E22689_;_IMAGE:306813 lung
CB118390.1 Clone L8SCK0-18-F09 liver 5' read
AI280391.1 Clone IMAGE:1880054 mixed 3' read
BP204713.1 Clone CAS03151 vascular 5' read P
BP293481.1 Clone LNG12211 lung 5' read P
DA335857.1 Clone BRHIP3036042 brain 5' read P
BG460242.1 connective tissue P
N79051.1 Clone IMAGE:306813 lung 3' read
W24195.1 Clone IMAGE:306789 lung 5' read
W24201.1 Clone IMAGE:306813 lung 5' read
AA913573.1 Clone IMAGE:1525202 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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