> Solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4)
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UGID:132619     UniGene Hs.10094     Homo sapiens (human)   SLC12A4 Order cDNA clone, Links
Solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4)

Human protein-coding gene SLC12A4. Represented by 450 ESTs from 179 cDNA libraries. Corresponds to 5 reference sequences (different isoforms). [UniGene 132619 - Hs.10094]

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with RefSeq proteins. The alignments can suggest function of the cluster.
Best Hits and Hits from model organismsSpeciesId(%)Len(aa)
NP_001139434.1 SLC12A4 gene product H. sapiens 100.0 1086
XP_003917118.1 PREDICTED: solute carrier family 12 member 4 isoform 1 P. anubis 99.9 1084
XP_001096326.2 PREDICTED: solute carrier family 12 member 4 isoform 3 M. mulatta 99.8 1078
XP_003315222.2 PREDICTED: LOW QUALITY PROTEIN: solute carrier family 12 member 4 P. troglodytes 99.7 1040
NP_033221.1 Slc12a4 gene product M. musculus 98.3 1084
XP_691291.2 PREDICTED: solute carrier family 12 member 4 D. rerio 89.7 1094
NP_726377.1 kazachoc, isoform D D. melanogaster 68.8 1069
NP_001255278.1 Protein KCC-2, isoform b C. elegans 57.0 1066
NP_174333.2 cation-chloride co-transporter 1 A. thaliana 50.9 273
Other hits (2 of 41) [Show all]SpeciesId(%)Len(aa)
XP_001498498.1 PREDICTED: solute carrier family 12 member 4-like isoform 1 E. caballus 99.1 1085
NP_999114.1 SLC12A4 gene product S. scrofa 99.1 1085

GENE EXPRESSION
Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.
EST Profile: Approximate expression patterns inferred from EST sources.
[Show more entries with profiles like this]
GEO Profiles: Experimental gene expression data (Gene Expression Omnibus).
cDNA Sources: brain; testis; placenta; eye; mammary gland; embryonic tissue; mixed; kidney; ovary; vascular; uterus; intestine; lung; uncharacterized tissue; connective tissue; thymus; skin; blood; cervix; liver; mouth; pancreas; larynx; spleen; prostate; trachea; muscle; epididymis; thyroid; lymph node; umbilical cord; bladder; ascites; nerve; bone; stomach; bone marrow; parathyroid
MAPPING POSITION
Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.
Chromosome: 16
Map position: 16q22.1
UniSTS entry: Chr 16 RH44404 [Map Viewer]
UniSTS entry: Chr 16 RH77895 [Map Viewer]
UniSTS entry: Chr 16 RH70676 [Map Viewer]
UniSTS entry: Chr 16 RH79953
UniSTS entry: Chr 16 RH70236 [Map Viewer]
UniSTS entry: Chr 16 SLC12A4_2007
UniSTS entry: Chr 16 ksks15
UniSTS entry: Chr 1 D10S16
SEQUENCES
Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (20)

AK124821.1 Homo sapiens cDNA FLJ42831 fis, clone BRCAN2018490
NM_005072.4 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4), transcript variant 1, mRNA PA
AK026911.1 Homo sapiens cDNA: FLJ23258 fis, clone COL05740, highly similar to HSKCC Human K-Cl cotransporter (hKCC1) mRNA PA
AY026038.1 Homo sapiens K-Cl cotransporter (SLC12A4) mRNA, partial cds P
BC021193.2 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4, mRNA (cDNA clone MGC:1455 IMAGE:3349710), complete cds PA
U55054.1 Human K-Cl cotransporter (hKCC1) mRNA, complete cds P
AK311073.1 Homo sapiens cDNA, FLJ18115 P
AK310027.1 Homo sapiens cDNA, FLJ17069
AK097808.1 Homo sapiens cDNA FLJ40489 fis, clone TESTI2044194, highly similar to Solute carrier family 12 member 4 P
AK293956.1 Homo sapiens cDNA FLJ56476 complete cds, highly similar to Solute carrier family 12 member 4 P
AK293906.1 Homo sapiens cDNA FLJ60065 complete cds, highly similar to Solute carrier family 12 member 4 P
AK299042.1 Homo sapiens cDNA FLJ55911 complete cds, highly similar to Solute carrier family 12 member 4 P
AK302790.1 Homo sapiens cDNA FLJ53419 complete cds, highly similar to Solute carrier family 12 member 4 P
AF053402.1 Homo sapiens erythrocyte K-Cl cotransporter mRNA, partial cds P
AK316415.1 Homo sapiens cDNA, FLJ79314 complete cds, highly similar to Solute carrier family 12 member 4 P
NM_001145964.1 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4), transcript variant 5, mRNA PA
NM_001145963.1 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4), transcript variant 4, mRNA PA
NM_001145962.1 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4), transcript variant 3, mRNA PA
NM_001145961.1 Homo sapiens solute carrier family 12 (potassium/chloride transporters), member 4 (SLC12A4), transcript variant 2, mRNA PA
AF047338.1 Homo sapiens erythroid K:Cl cotransporter (KCC1) mRNA, complete cds P

EST sequences (10 of 450) [Show all sequences]

AA905663.1 Clone IMAGE:1506293 mixed 3' read
AA993866.1 Clone IMAGE:1625129 embryonic tissue 3' read P
AA908958.1 Clone IMAGE:1523093 mixed 3' read P
AI004056.1 Clone IMAGE:1619900 testis 3' read
AI014523.1 Clone IMAGE:1628030 mixed 3' read P
AI034026.1 Clone IMAGE:1646818 parathyroid 3' read P
AI053532.1 Clone IMAGE:1861995 ovary 3' read A
AI054054.1 Clone IMAGE:1861449 ovary 3' read A
AI125379.1 Clone IMAGE:1736589 testis 3' read P
AI143461.1 Clone IMAGE:1690702 mixed 3' read


Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria

 
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