3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) (HMGCS2)

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Finding cDNAs

UGID:37122 UniGene Bt.9689 Bos taurus (cow) HMGCS2

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3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) (HMGCS2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001039348.1	hydroxymethylglutaryl-CoA synthase 2 precursor	B. taurus	100.0	507
NP_005509.1	hydroxymethylglutaryl-CoA synthase 2 precursor	H. sapiens	90.8	507
NP_032282.2	hydroxymethylglutaryl-CoA synthase 2 precursor	M. musculus	89.6	507
NP_001087380.1	MGC80816 protein	X. laevis	74.7	471
NP_957379.1	hydroxymethylglutaryl-CoA synthase 1	D. rerio	73.7	482
NP_524711.1	HMG coenzyme A synthase, isoform A	D. melanogaster	70.2	456
XP_323241.1	probable hydroxymethylglutaryl-CoA synthase [MIPS]	N. crassa	57.7	449
NP_192919.1	MVA1; acetyl-CoA C-acetyltransferase/ hydroxymethylglutaryl-CoA synthase	A. thaliana	56.4	449
NP_013580.1	3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis; Erg13p	S. cerevisiae	55.6	448
XP_001695871.1	hypothetical protein CHLREDRAFT_118594	C. reinhardtii	51.4	179
NP_504496.1	hypothetical protein F25B4.6	C. elegans	51.0	433

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	Restricted Expression:	calf [show more like this]
	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	cDNA Sources:	rumen; liver; mixed; abomasum; intestine; other; omasum; testis; reticulum

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (3)

AJ888382.1	Bos taurus partial mRNA for 3-hydroxy-3-methylglutaryl-coenzyme A synthase (hmgCoA gene)	P
BC112666.1	Bos taurus 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial), mRNA (cDNA clone MGC:137181 IMAGE:8026620), complete cds	PA
NM_001045883.1	Bos taurus 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, mRNA	PA

EST sequences (10 of 171) [Show all sequences]

BM433613.1		omasum
BM434377.1		reticulum		A
CB170957.1		other		A
BP104154.1	Clone ORCS25450	liver	3' read	A
BP104183.1	Clone ORCS25489	liver	3' read	A
BP105183.1	Clone ORCS26729	liver	3' read	A
BP106638.1	Clone ORCS28596	liver	3' read	A
CB226674.1		rumen
CB227202.1		rumen
CB227311.1		rumen		A

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria