Aminolevulinate, delta-, synthase 2 (ALAS2)

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Finding cDNAs

UGID:1747180 UniGene Bt.49467 Bos taurus (cow) ALAS2

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Aminolevulinate, delta-, synthase 2 (ALAS2)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001030275.1	5-aminolevulinate synthase 2 precursor	B. taurus	100.0	586
NP_000023.2	5-aminolevulinate synthase 2 isoform a precursor	H. sapiens	95.2	586
NP_033783.1	5-aminolevulinate synthase 2 isoform a	M. musculus	93.2	586
NP_001087499.1	MGC82115 protein	X. laevis	79.6	607
NP_571757.1	5-aminolevulinate synthase 2 precursor	D. rerio	78.0	578
NP_477281.1	aminolevulinate synthase	D. melanogaster	69.7	499
XP_326044.1	hypothetical protein ( (AB071862) 5-aminolevulinate synthase [Gibberella fujikuroi] )	N. crassa	55.8	409
NP_010518.1	5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; Hem1p	S. cerevisiae	47.7	428

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	Restricted Expression:	fetus [show more like this]
	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	cDNA Sources:	mixed; reticulum; kidney; lung; uncharacterized tissue; brain; uterus; liver; skin

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	BC102938.1	Bos taurus aminolevulinate, delta-, synthase 2, mRNA (cDNA clone MGC:128330 IMAGE:7989379), complete cds	PA
	NM_001035103.1	Bos taurus aminolevulinate, delta-, synthase 2 (ALAS2), nuclear gene encoding mitochondrial protein, mRNA	PA

EST sequences (10 of 53) [Show all sequences]

AV600913.1	Clone E1KI001C07	kidney	3' read	P
AV600914.1	Clone E1KI001C07	kidney	5' read	P
AV603378.1	Clone E1KI015H03	kidney	3' read	P
AV603379.1	Clone E1KI015H03	kidney	5' read	P
AV605417.1	Clone E1KI028F08	kidney	3' read	P
AV605418.1	Clone E1KI028F08	kidney	5' read	P
BM286120.1		mixed	5' read	P
BP105888.1	Clone ORCS27604	liver	3' read	PA
CK776354.1		mixed	3' read	PA
CN442050.1	Clone BE04028A1B06	mixed	5' read	P

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria