5,10-methylenetetrahydrofolate reductase (NADPH) (MTHFR)

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Finding cDNAs

UGID:1209463 UniGene Bt.26830 Bos taurus (cow) MTHFR

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5,10-methylenetetrahydrofolate reductase (NADPH) (MTHFR)

SELECTED PROTEIN SIMILARITIES

Comparison of sequences in UniGene with selected protein reference sequences. The alignments can suggest function of a gene.

Reference Protein		Species	Id(%)	Len(aa)
NP_001011685.1	5,10-methylenetetrahydrofolate reductase	B. taurus	100.0	654
NP_005948.3	5,10-methylenetetrahydrofolate reductase	H. sapiens	93.1	655
NP_034970.2	5,10-methylenetetrahydrofolate reductase isoform b	M. musculus	92.8	653
NP_001080092.1	5,10-methylenetetrahydrofolate reductase	X. laevis	84.8	638
XP_001922554.1	PREDICTED: wu:fa92h12	D. rerio	82.8	638
NP_741028.1	hypothetical protein C06A8.1	C. elegans	52.3	611
XP_001702476.1	5,10-methylenetetrahydrofolate reductase	C. reinhardtii	46.7	582
XP_328396.1	hypothetical protein	N. crassa	46.3	579
NP_191556.1	MTHFR1 (METHYLENETETRAHYDROFOLATE REDUCTASE 1); methylenetetrahydrofolate reductase (NADPH)	A. thaliana	45.7	578

GENE EXPRESSION

Tissues and development stages from this gene's sequences survey gene expression. Links to other NCBI expression resources.

	EST Profile:	Approximate expression patterns inferred from EST sources. [Show more entries with profiles like this]
	cDNA Sources:	mixed; blood; brain; kidney; uterus; lymphoreticular; uncharacterized tissue; muscle; mammary gland; cartilage; liver; testis; extraembryonic tissue

MAPPING POSITION

Genomic location specified by transcript mapping, radiation hybrid mapping, genetic mapping or cytogenetic mapping.

Chromosome:

SEQUENCES

Sequences representing this gene; mRNAs, ESTs, and gene predictions supported by transcribed sequences.

mRNA sequences (2)

	AY854631.1	Bos taurus methylenetetrahydrofolate reductase (MTHFR) mRNA, complete cds	P
	NM_001011685.1	Bos taurus 5,10-methylenetetrahydrofolate reductase (NADPH) (MTHFR), mRNA	P

EST sequences (10 of 48) [Show all sequences]

AW326208.1		mixed	5' read
AW445584.1		mixed	5' read
AW478874.1		mixed	5' read	P
AW480618.1		mixed	5' read
AW484848.1		mixed	5' read	P
AW631894.1		mixed	5' read
AW658667.1		mixed	5' read	P
AV593414.1	Clone E1CA007D10	cartilage	5' read
AV593449.1	Clone E1CA007F08	cartilage	3' read
AV593450.1	Clone E1CA007F08	cartilage	5' read

Key to Symbols

P Has similarity to known Proteins (after translation)
A Contains a poly-Adenylation signal
S Sequence is a Suboptimal member of this cluster
M Clone is putatively CDS-complete by MGC criteria