On Jun 20, 2008 this sequence version replaced gi:74230343.
The Escherichia coli B7A whole genome shotgun (WGS) project has the project accession AAJT00000000. This version of the project (02) has the accession number AAJT02000000, and consists of sequences AAJT02000001-AAJT02000289.
Escherichia coli B7A is a standard enterotoxigenic E. coli (ETEC) isolate that was obtained from Maj. Carl Brinkley (Walter Reed Army Institute of Research). ETEC is the leading cause of traveler's diarrhea, which is chiefly characterized by a large volume of watery diarrhea. ETEC primarily colonizes the small intestine by way of the pili. Additionally, two toxins are thought to be responsible for the virulence: heat-stable and heat-labile enterotoxins. The stock used for genomic DNA preparation was obtained from a master- and production cGMP cell bank available at WRAIR/NMRC. Pathogenicity has been confirmed in human challenge experiments. Other known virulence factors include: serotype O148:H28, heat-stable toxin and heat-labile toxin, and CFA type CS6. Additionally, this isolate contains multiple plasmids.
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