1H08: Cdk2 In Complex With A Disubstituted 2, 4-Bis Anilino Pyrimidine Cdk4 Inhibitor

PDB ID: 1H08Download
MMDB ID: 91108
PDB Deposition Date: 2002/6/11
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 1H08: monomeric; determined by author and by software (PISA)
Molecular Components in 1H08
Label Count Molecule
Protein (1 molecule)
1
Cell Division Protein Kinase 2
(Gene symbol: CDK2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(2r)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol(2r)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol
2
1
(2s)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol(2s)-1-{4-[(4-anilino-5-bromopyrimidin-2-yl)amino]phenoxy}-3-(dimethylamino)propan-2-ol
3
1
GlycerolGlycerin; Propane-1,2,3-triol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303