Crystal Structure of the Second Bromodomain of Human Brd2 in Complex With the Inhibitor JQ1
MMDB ID: 85388PDB ID: 3ONIhelp
PDB Deposition Date: 2010/8/29help
Updated in MMDB: 03/2012  help
Experimental Method:
X-Ray Diffraction help
Resolution: 1.61  Åhelp
Source Organism:
Similar Structures: help
Citation: help
Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, Mckeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE
Nature (2010) 468 p.1067
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Biological Unit: monomeric; determined by authorhelp
Interactions?
schmatic for structure MMDB ID=85388 biounit 1
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Molecular graphic for MMDB ID 85388 biounit 1
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Notice
ProteinChemical
Molecules and interactionshelp
Label Count Molecule Interactions
Protein and interactions (1 molecule)
1
Bromodomain Containing 2, Isoform Cra_a
Show annotation
  • Ethylene Glycol
  • JQ1
  • Nickel (Ii) Ion
Chemicals and interactions (5 molecules)
 -Click for PubChem compound information. 1
  • Bromodomain Containing 2, Isoform Cra_a
 -Click for PubChem compound information. 2
  • Bromodomain Containing 2, Isoform Cra_a
 -Click for PubChem compound information. 2
  • Bromodomain Containing 2, Isoform Cra_a
* Click molecule labels to explore molecular sequence information.

Citing MMDB
Madej T, Addess KJ, Fong JH, Geer LY, Geer RC, Lanczycki CJ, Liu C, Lu S, Marchler-Bauer A, Panchenko AR, Chen J, Thiessen PA, Wang Y, Zhang D, Bryant SH. "MMDB: 3D structures and macromolecular interactions." Nucleic Acids Res. 2012 Jan; 40(Database issue):D461-4
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