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3BJC:
Crystal structure of the PDE5A catalytic domain in complex with a novel inhibitor
PDB ID:
3BJC
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MMDB ID:
64178
PDB Deposition Date:
2007/12/3
Updated in MMDB:
2011/05
Experimental Method:
x-ray diffraction
Resolution:
2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3BJC: monomeric; determined by author and by software (PISA)
Molecular Components in 3BJC
Label
Count
Molecule
Protein (1 molecule)
A
1
Cgmp-specific 3',5'-cyclic Phosphodiesterase
(Gene symbol:
PDE5A
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC ION
2
1
MAGNESIUM ION
3
1
5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303