5U62: Crystal structure of EED in complex with H3K27Me3 peptide and 6-(benzo[d][1,3]dioxol-4-ylmethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine

PDB ID: 5U62Download
MMDB ID: 146395
PDB Deposition Date: 2016/12/7
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 5U62: dimeric; determined by author and by software (PISA)
Molecular Components in 5U62
Label Count Molecule
Proteins (2 molecules)
1
Polycomb Protein EED
(Gene symbol: EED)
Molecule annotation
1
Histone-lysine N-methyltransferase Ezh2
(Gene symbol: EZH2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
GLYCEROLGLYCEROL
2
2
YTTRIUM (III) IONYTTRIUM (III) ION
3
1
(6S)-6-[(2H-1,3-benzodioxol-4-yl)methyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine(6S)-6-[(2H-1,3-benzodioxol-4-yl)methyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303