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4O13:
The crystal structure of NAMPT in complex with GNE-618
PDB ID:
4O13
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MMDB ID:
124035
PDB Deposition Date:
2013/12/15
Updated in MMDB:
2014/10
Experimental Method:
x-ray diffraction
Resolution:
1.75 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4O13: dimeric; determined by author and by software (PISA)
Molecular Components in 4O13
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Nicotinamide Phosphoribosyltransferase
(Gene symbol:
NAMPT
)
Chemicals and Non-standard biopolymers (14 molecules)
1
2
N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide
2
4
PHOSPHATE ION
3
8
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303