4IDT: Crystal Structure of NIK with 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine (T28)

PDB ID: 4IDTDownload
MMDB ID: 109223
PDB Deposition Date: 2012/12/13
Updated in MMDB: 2018/06
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4IDT: dimeric; determined by author and by software (PISA)
Molecular Components in 4IDT
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase 14
(Gene symbol: MAP3K14)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303