2LF6: Solution NMR structure of HopABPph1448_220_320 from Pseudomonas syringae pv. phaseolicola str. 1448A, Midwest Center for Structural Genomics target APC40132.4 and Northeast Structural Genomics Consortium target PsT3A

HopPmaL is a member of the HopAB family of type III effectors present in the phytopathogen Pseudomonas syringae. Using both X-ray crystallography and solution nuclear magnetic resonance, we demonstrate that HopPmaL contains two structurally homologous yet functionally distinct domains. The N-terminal domain corresponds to the previously described Pto-binding domain, while the previously uncharacterised C-terminal domain spans residues 308-385. While structurally similar, these domains do not share significant sequence similarity and most importantly demonstrate significant differences in key residues involved in host protein recognition, suggesting that each of them targets a different host protein.
PDB ID: 2LF6Download
MMDB ID: 91503
PDB Deposition Date: 2011/6/28
Updated in MMDB: 2011/07
Experimental Method:
solution nmr
Source Organism:
Similar Structures:
Biological Unit for 2LF6: monomeric; determined by author
Molecular Components in 2LF6
Label Count Molecule
Protein (1 molecule)
Effector Protein Hopab1
Molecule annotation
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Citing MMDB