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2HS1:
Ultra-high resolution X-ray crystal structure of HIV-1 protease V32I mutant with TMC114 (darunavir) inhibitor
PDB ID:
2HS1
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MMDB ID:
41692
PDB Deposition Date:
2006/7/20
Updated in MMDB:
2021/10
Experimental Method:
x-ray diffraction
Resolution:
0.84 Å
Source Organism:
Human immunodeficiency virus 1
Similar Structures:
VAST+
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Biological Unit for 2HS1: dimeric; determined by author and by software (PISA,PQS)
Molecular Components in 2HS1
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Hiv-1 Protease
Chemicals and Non-standard biopolymers (6 molecules)
1
3
CHLORIDE ION
2
2
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
3
1
DIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303