Crystal Structure of the Human Sialidase Neu2 in Complex With 3- Hydroxypropyl Ether Mimetic Inhibitor
MMDB ID: 42719PDB ID: 2F12help
PDB Deposition Date: 2005/11/14help
Updated in MMDB: 11/2012  help
Experimental Method:
X-Ray Diffraction help
Resolution: 2.27  Åhelp
Source Organism:
Similar Structures: help
Citation: help
Crystal structure of the human sialidase neu2 in complex with 3- hydroxypropyl ether mimetic inhibitor.
Chavas LMG, Kato R, Mann MC, Thomson RJ, Dyason JC, Von Itzstein M, Fusi P, Tringali C, Venerando B, Tettamanti G, Monti E, Wakatsuki S
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Biological Unit: monomeric; determined by authorhelp
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schmatic for structure MMDB ID=42719 biounit 1
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Molecular graphic for MMDB ID 42719 biounit 1
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ProteinChemical
Molecules and interactionshelp
Label Count Molecule Interactions
Protein and interactions (1 molecule)
1
Sialidase 2
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  • HyDROXYPROPYLEtHERMiMETIC
  • Phosphate Ion
Chemicals and interactions (2 molecules)
 -Click for PubChem compound information. 1
  • Sialidase 2
 -Click for PubChem compound information. 1
  • Sialidase 2
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Citing MMDB
Madej T, Addess KJ, Fong JH, Geer LY, Geer RC, Lanczycki CJ, Liu C, Lu S, Marchler-Bauer A, Panchenko AR, Chen J, Thiessen PA, Wang Y, Zhang D, Bryant SH. "MMDB: 3D structures and macromolecular interactions." Nucleic Acids Res. 2012 Jan; 40(Database issue):D461-4
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