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| Reference: |
Gallagher DT, Gilliland GL, Xiao G, Zondlo J, Fisher KE, Chinchilla D, Eisenstein EStructure and control of pyridoxal phosphate dependent allosteric threonine deaminaseStructure v6, p.465-475BACKGROUND: Feedback inhibition of biosynthetic threonine deaminase (TD) from Escherichia coli provided one of the earliest examples of protein-based metabolic regulation. Isoleucine, the pathway end-product, and valine, the product of a parallel pathway, serve as allosteric inhibitor and activator, respectively. This enzyme is thus a useful model system for studying the structural basis of allosteric control mechanisms....
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| Description: |
Threonine Deaminase (Biosynthetic) From E. Coli. |
| Deposition: |
1998/3/27   |
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| Author: |
Gallagher DT, Gilliland GL, Xiao G, Eisenstein E |
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| Taxonomy: |
Escherichia coli |
| Related Structure: |
VAST |
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Molecular components in the MMDB structure are listed below and may include macromolecular chains, 3D domains, protein classifications (domain families), and ligands, as available. Mouse over each icon for more information on the component.  | Ligand |
![Synonyms: Pyridoxamine-P,pyridoxamine phosphate,Pyridoxamine 5-phosphate,pyridoxamine 5'-phosphate,PYRIDOXAMINE-5'-PHOSPHATE,1zc9,Pyridoxamine phosphate [JAN],bmse000131,Pyridoxamine, dihydrogen phosphate,UNII-Q05R77UO7P,951-83-7 (hydrochloride),82890_FLUKA,82890_SIGMA,CHEBI:18335,EINECS 208-471-6,Pyridoxamine, 3-(dihydrogen phosphate)... -Click for PubChem compound information](http://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?cid=1053) |
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pyridoxamine ph.. |
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1 occurrence |
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Citing MMDB:
Wang Y, Addess KJ, Chen J, Geer LY, He J, He S, Lu S, Madej T, Marchler-Bauer A, Thiessen PA, Zhang N, Bryant SH.
"MMDB: annotating protein sequences with Entrez's 3D-structure database.",
Nucleic Acids Res. 2007 Jan; 35(Database issue): D298-300.
Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH.
"MMDB: Entrez's 3D-structure database", Nucleic Acids Res. 2003 Jan; 31(1): 474-7.
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