Multi-domain Organization of the Hnf4alpha Nuclear Receptor Complex on DNA
MMDB ID: 108487PDB ID: 4IQRhelp
PDB Deposition Date: 2013/1/13help
Updated in MMDB: 10/2013  help
Experimental Method:
X-Ray Diffraction help
Resolution: 2.9  Åhelp
Source Organism:
synthetic construct ▼help
Similar Structures: help
Citation: help
Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F
Nature (2013) 495 p.394
  • help
Biological Unit: hexameric; determined by author, and by software (PISA)help
Interactions?
schmatic for structure MMDB ID=108487 biounit 1
Molecular Graphic ?
Molecular graphic for MMDB ID 108487 biounit 1
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ProteinNucleotideChemical
Molecules and interactionshelp
Label Count Molecule Interactions
Proteins and interactions (4 molecules)
2
Hepatocyte Nuclear Factor 4-alpha
Show annotation
  • DNA (5'-10 D(*gp*gp*ap*ap*cp*tp*ap*gp*gp*tp*cp*ap*
    ap*ap*gp*gp*tp*cp*ap*g)-3')
  • DNA (5'-15 D(*cp*cp*tp*gp*ap*cp*cp*tp*tp*tp*gp*ap*
    cp*cp*tp*ap*gp*tp*tp*c)-3')
  • Hepatocyte Nuclear Factor 4-alpha
  • Myristic Acid
  • Nuclear Receptor Coactivator 2
  • Zinc Ion
2
Nuclear Receptor Coactivator 2
Show annotation
  • Hepatocyte Nuclear Factor 4-alpha
Nucleotides and interactions (2 molecules)
1
DNA (5'-10 D(*gp*gp*ap*ap*cp*tp*ap*gp*gp*tp*cp*ap*
ap*ap*gp*gp*tp*cp*ap*g)-3')
  • DNA (5'-15 D(*cp*cp*tp*gp*ap*cp*cp*tp*tp*tp*gp*ap*
    cp*cp*tp*ap*gp*tp*tp*c)-3')
  • Hepatocyte Nuclear Factor 4-alpha
1
DNA (5'-15 D(*cp*cp*tp*gp*ap*cp*cp*tp*tp*tp*gp*ap*
cp*cp*tp*ap*gp*tp*tp*c)-3')
  • DNA (5'-10 D(*gp*gp*ap*ap*cp*tp*ap*gp*gp*tp*cp*ap*
    ap*ap*gp*gp*tp*cp*ap*g)-3')
  • Hepatocyte Nuclear Factor 4-alpha
Chemicals and interactions (6 molecules)
 -Click for PubChem compound information. 2
  • Hepatocyte Nuclear Factor 4-alpha
 -Click for PubChem compound information. 4
  • Hepatocyte Nuclear Factor 4-alpha
* Click molecule labels to explore molecular sequence information.

Citing MMDB
Madej T, Addess KJ, Fong JH, Geer LY, Geer RC, Lanczycki CJ, Liu C, Lu S, Marchler-Bauer A, Panchenko AR, Chen J, Thiessen PA, Wang Y, Zhang D, Bryant SH. "MMDB: 3D structures and macromolecular interactions." Nucleic Acids Res. 2012 Jan; 40(Database issue):D461-4
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