Crystal Structure of Ammosamide 272:myosin-2 Motor Domain Complex
MMDB ID: 106647PDB ID: 4AE3help
PDB Deposition Date: 2012/1/5help
Updated in MMDB: 01/2013help
Experimental Method:
X-Ray Diffraction help
Resolution: 2.5  Åhelp
Source Organism:
Similar Structures: help
Citation: help
Structural basis for ammosamide mediated myosin motor activity inhibition.
Chinthalapudi K, Heissler SM, Fenical W, Manstein DJ
No recorded citation in PubMed
  • help
Biological Unit: monomeric; determined by author, and by software (PISA)help
schmatic for structure MMDB ID=106647 biounit 1
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Molecular graphic for MMDB ID 106647 biounit 1
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Molecules and interactionshelp
Label Count Molecule Interactions
Protein and interactions (1 molecule)
Myosin-2 Heavy Chain
Show annotation
  • Adp Orthovanadate
  • Ammosamide 272
  • Ethylene Glycol
  • Magnesium Ion
Chemicals and interactions (8 molecules)
 -Click for PubChem compound information. 1
  • Magnesium Ion
  • Myosin-2 Heavy Chain
 -Click for PubChem compound information. 1
  • Adp Orthovanadate
  • Myosin-2 Heavy Chain
 -Click for PubChem compound information. 2
  • Myosin-2 Heavy Chain
 -Click for PubChem compound information. 4
  • Myosin-2 Heavy Chain
* Click molecule labels to explore molecular sequence information.

Citing MMDB
Madej T, Addess KJ, Fong JH, Geer LY, Geer RC, Lanczycki CJ, Liu C, Lu S, Marchler-Bauer A, Panchenko AR, Chen J, Thiessen PA, Wang Y, Zhang D, Bryant SH. "MMDB: 3D structures and macromolecular interactions." Nucleic Acids Res. 2012 Jan; 40(Database issue):D461-4
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