Structure Summary, 7PTI, 3378

PDB ID: 7PTI

Reference:

Eigenbrot C, Randal M, Kossiakoff AAStructural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 AProtein Eng. v3, p.591-598

The X-ray structure of a variant of basic pancreatic trypsin inhibitor (BPTI) has been analyzed to determine the structural accommodation resulting from removal of a disulfide cross-link in a protein. The disulfide removed, Cys30-Cys51, has been implicated in both the folding pathway of the protein and its overall thermal stability....

» View full abstract

Description:

Bovine Pancreatic Trypsin Inhibitor (BPTI) Mutant (Cys 30 Replaced By Ala, Cys 51 Replaced By Ala) (C30A, C51A).

Deposition:

1990/3/8

Taxonomy:

Bos taurus

Molecular components in the MMDB structure are listed below and may include macromolecular chains, 3D domains, protein classifications (domain families), and ligands, as available. Mouse over each icon for more information on the component. Click to see help

Citing MMDB:

Wang Y, Addess KJ, Chen J, Geer LY, He J, He S, Lu S, Madej T, Marchler-Bauer A, Thiessen PA, Zhang N, Bryant SH. "MMDB: annotating protein sequences with Entrez's 3D-structure database.", Nucleic Acids Res. 2007 Jan; 35(Database issue): D298-300.

Chen J, Anderson JB, DeWeese-Scott C, Fedorova ND, Geer LY, He S, Hurwitz DI, Jackson JD, Jacobs AR, Lanczycki CJ, Liebert CA, Liu C, Madej T, Marchler-Bauer A, Marchler GH, Mazumder R, Nikolskaya AN, Rao BS, Panchenko AR, Shoemaker BA, Simonyan V, Song JS, Thiessen PA, Vasudevan S, Wang Y, Yamashita RA, Yin JJ, Bryant SH. "MMDB: Entrez's 3D-structure database", Nucleic Acids Res. 2003 Jan; 31(1): 474-7.