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MMDB ID: 20766
PDB ID: 1GNG
Reference: Bax B, Carter PS, Lewis C, Guy AR, Bridges A, Tanner R, Pettman G, Mannix C, Culbert AA, Brown MJ, Smith DG, Reith ADThe structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylationStructure v9, p.1143-1152
BACKGROUND: Glycogen synthase kinase-3 (GSK-3) sequentially phosphorylates four serine residues on glycogen synthase (GS), in the sequence SxxxSxxxSxxx-SxxxS(p), by recognizing and phosphorylating the first serine in the sequence motif SxxxS(P) (where S(p) represents a phosphoserine). FRATtide (a peptide derived from a GSK-3 binding protein) binds to GSK-3 and blocks GSK-3 from interacting with Axin....
Description: Glycogen Synthase Kinase-3 Beta (Gsk3) Complex With Frattide Peptide.
Deposition: 2001/10/4 Click for more information 
Taxonomy:
Chain A, B:Homo sapiens
Related Structure: VAST
Molecular components in the MMDB structure are listed below and may include macromolecular chains, 3D domains, protein classifications (domain families), and ligands, as available. Mouse over each icon for more information on the component.Click to see help




 

 

Ligand
Synonyms: SULFURIC ACID,Sulphuric acid,Schwefelsaeure,Mattling acid,Battery acid,Dipping acid,Electrolyte acid,Hydrogen sulfate,sulfate,Oil of vitreol,Oil of vitriol,Acidum sulfuricum,Acido solforico,Acido sulfurico,Dihydrogen sulfate,Acide sulfurique,Vitriol Brown Oil,Sulfuric acid, spent,Methanolic H2SO4... -Click for PubChem compound information Zoom the image
sulfuric acid
 
4 occurrences
Synonyms: Tris,TROMETHAMINE,Tham,Trometamol,Tris buffer,Trisaminol,Trispuffer,Tromethane,Trisamine,Pehanorm,Talatrol,Trizma,Tutofusin tris,Apiroserum Tham,Tris-steril,Addex-tham,Tris, free base,Tris-base,Trometamolum,Tromethamolum,Tromethanmin,Tris Amino,Trisamin,Tris base,Tris-Amino,Trometamole,Aminotrimethylolmethane... -Click for PubChem compound information Zoom the image
Tromethamine
 
1 occurrence
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