5M6M: Small Molecule Inhibitors Of Iap

PDB ID: 5M6MDownload
MMDB ID: 151026
PDB Deposition Date: 2016/10/25
Updated in MMDB: 2017/06
Experimental Method:
x-ray diffraction
Resolution: 2.37  Å
Source Organism:
Similar Structures:
Biological Unit for 5M6M: monomeric; determined by author and by software (PISA)
Molecular Components in 5M6M
Label Count Molecule
Protein (1 molecule)
1
E3 Ubiquitin-protein Ligase Xiap
(Gene symbol: XIAP)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Zinc IonZinc Ion
2
1
Sodium IonSodium Ion
3
1
1-[[(2~{r},5~{r})-1-[2-[3,3-Dimethyl-6-(Phenylmethyl)-2~{h}-Pyrrolo[3,2-B]pyridin-1-Yl]-2-Oxidanylidene-Ethyl]-5-Methyl-Piperazin-4-Ium-2-Yl]methyl]pyrrolidin-2-One1-[[(2~{r},5~{r})-1-[2-[3,3-Dimethyl-6-(Phenylmethyl)-2~{h}-Pyrrolo[3,2-B]pyridin-1-Yl]-2-Oxidanylidene-Ethyl]-5-Methyl-Piperazin-4-Ium-2-Yl]methyl]pyrrolidin-2-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303