4FS4: Structure Of Bace Bound To (s)-4-(3'-methoxy-[1,1'-biphenyl]-3-yl)-1, 4-dimethyl-6-oxotetrahydropyrimidin-2(1h)-iminium

PDB ID: 4FS4Download
MMDB ID: 103808
PDB Deposition Date: 2012/6/26
Updated in MMDB: 2012/10
Experimental Method:
x-ray diffraction
Resolution: 1.74  Å
Source Organism:
Similar Structures:
Biological Unit for 4FS4: dimeric; determined by author
Molecular Components in 4FS4
Label Count Molecule
Proteins (2 molecules)
2
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
(6s)-2-Amino-6-(3'-Methoxybiphenyl-3-Yl)-3,6-Dimethyl-5,6-Dihydropyrimidin-4(3h)-One(6s)-2-Amino-6-(3'-Methoxybiphenyl-3-Yl)-3,6-Dimethyl-5,6-Dihydropyrimidin-4(3h)-One
2
2
L(+)-Tartaric AcidL(+)-Tartaric Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303