4JDS: SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine

PDB ID: 4JDSDownload
MMDB ID: 108734
PDB Deposition Date: 2013/2/25
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 4JDS: dimeric; determined by software (PISA)
Molecular Components in 4JDS
Label Count Molecule
Proteins (2 molecules)
2
Histone-lysine N-methyltransferase Setd7
(Gene symbol: SETD7)
Molecule annotation
Chemicals and Non-standard biopolymers (28 molecules)
1
2
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
2
N-[(2R)-3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl]-8-fluoro-1,2,3,4-tetrahydroisoquinoline-6-sulfonamideN-[(2R)-3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl]-8-fluoro-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide
3
24
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303