4BCI: Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor

PDB ID: 4BCIDownload
MMDB ID: 175510
PDB Deposition Date: 2012/10/2
Updated in MMDB: 2019/06
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4BCI: dimeric; determined by software (PISA)
Molecular Components in 4BCI
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 9
(Gene symbol: CDK9)
Molecule annotation
1
Cyclin-t1
(Gene symbol: CCNT1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303