3Q77: Structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor

PDB ID: 3Q77Download
MMDB ID: 90471
PDB Deposition Date: 2011/1/4
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.998  Å
Source Organism:
Similar Structures:
Biological Unit for 3Q77: monomeric; determined by author and by software (PISA)
Molecular Components in 3Q77
Label Count Molecule
Protein (1 molecule)
1
Neutrophil Elastase
(Gene symbol: ELANE)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-L-fucopyranosealpha-L-fucopyranose
3
1
2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate2-hydroxyethyl (4R)-4-(4-cyanophenyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303