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2FCI:
Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase
PDB ID:
2FCI
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MMDB ID:
161717
PDB Deposition Date:
2005/12/12
Updated in MMDB:
2023/11
Experimental Method:
solution nmr
Source Organism:
synthetic construct
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Taxonomy
Molecule
synthetic construct
B
Bos taurus
A
Similar Structures:
VAST+
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Molecular Components in 2FCI
Label
Count
Molecule
Proteins (2 molecules)
B
1
Doubly Phosphorylated Peptide Derived From SYK Kinase Comprising Residues 338-350
A
1
C-termainl SH2 Domain From Phospholipase C-gamma-1 Comprising Residues 663-759
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303