3SQF: Crystal Structure of Monomeric M-pmv Retroviral Protease

Following the failure of a wide range of attempts to solve the crystal structure of M-PMV retroviral protease by molecular replacement, we challenged players of the protein folding game Foldit to produce accurate models of the protein. Remarkably, Foldit players were able to generate models of sufficient quality for successful molecular replacement and subsequent structure determination. The refined structure provides new insights for the design of antiretroviral drugs.
PDB ID: 3SQFDownload
MMDB ID: 93764
PDB Deposition Date: 2011/7/5
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 3SQF: monomeric; determined by author
Molecular Components in 3SQF
Label Count Molecule
Protein (1 molecule)
Molecule annotation
* Click molecule labels to explore molecular sequence information.

Citing MMDB