Crystal Structure of the First Bromodomain of Human Brd4 in Complex With Ibet Inhibitor
MMDB ID: 86336PDB ID: 3P5Ohelp
PDB Deposition Date: 2010/10/9help
Updated in MMDB: 05/2011  help
Experimental Method:
X-Ray Diffraction help
Resolution: 1.6  Åhelp
Source Organism:
Similar Structures: help
Citation: help
Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung C, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A
Nature (2010) 468 p.1119
  • help
Biological Unit: monomeric; determined by author, and by software (PISA)help
schmatic for structure MMDB ID=86336 biounit 1
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Molecular graphic for MMDB ID 86336 biounit 1
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Data Set:
Molecules and interactionshelp
Label Count Molecule Interactions
Protein and interactions (1 molecule)
Bromodomain-containing Protein 4
Show annotation
  • EAM
  • Ethylene Glycol
Chemicals and interactions (4 molecules)
 -Click for PubChem compound information. 1
  • Bromodomain-containing Protein 4
  • Ethylene Glycol
 -Click for PubChem compound information. 3
  • Bromodomain-containing Protein 4
  • EAM
* Click molecule labels to explore molecular sequence information.

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